When your patients pressure is in the toilet fluid resuscitation can only take you so far in certain clinical scenarios, and occasionally a vasoactive agent must used to keep them out of the morgue. NYC paramedics are getting a new vasopressor added to their tool box for treating the critically ill. In this episode we will briefly review Norepinephrine, and make comparisons to Dopamine ( previously the only approved vasopressor infusion in the NYC region). Additionally, the protocols that Norepinephrine will appear in will be reviewed along with any possible safety concerns associated with its use. Lastly, the logistics of actually setting up the drip with use of a dial-a-flow will be covered. Whether you’re a NYC Medic who is getting Norepinephrine on the truck soon or you’ve already had it in your system this should be a nice review of a potentially life saving pressor.