Since before any of us did a manual defibrillation, cracked any ribs while
doing compressions, or drilled that first I.O., epinephrine had been used
by all of those medics that have come before us on countless cardiac
arrests. Epinephrine has been around forever as is practically ubiquitous
for the treatment of cardiac arrest. The question is should it be? The
P.A.R.A.M.E.D.I.C.-2 trial was just published in the New England Journal of
Medicine this week and it is further confirming the suspicions of many that
the “Amp of Epi” for every adult arrest is potentially more harmful than
helpful. Take a listen and decide for yourself.
https://www.nejm.org/doi/full/10.1056/NEJMoa1806842
References:
A Myth Revisited: Epinephrine for Cardiac Arrest. (2017, May 23). Retrieved
July 21, 2018, from
http://www.emdocs.net/myth-revisited-epinephrine-cardiac-arrest/
Morgenstern, J. (2018, July 21). Paramedic 2: Epinephrine harms/helps in
out of hospital cardiac arrest. Retrieved July 21, 2018, from
https://first10em.com/paramedic2/#more-6140
Perkins, G. D., Ji, C., Deakin, C. D., Quinn, T., Nolan, J. P., Scomparin,
C., . . . Lall, R. (2018). A Randomized Trial of Epinephrine in
Out-of-Hospital Cardiac Arrest. New England Journal of Medicine.
doi:10.1056/nejmoa1806842
Spiegel, R. (2018, July 20). EM Nerd-The Case of the Costly Compound.
Retrieved July 21, 2018, from
https://emcrit.org/emnerd/em-nerd-the-case-of-the-costly-compound/