Periprosthetic infection remains a main complication in arthroplasty.
In case of a possible infection the surgeon needs to have a concept of treatment which can be individually adjusted.
In early and secondary infections, component retention can be successful and sometimes is the only choice also in chronic infections. Surgical debridement is the key for success.
To increase the success of implant retaining surgery, V.A.C.Instill� therapy as a combination of negative pressure therapy and suction drainage, was performed in 35 patients with peri-prosthetic hip infection. Polyhexanide solution was used for irrigation. Definitive wound closure was possible following 2.1 V.A.C.� exchange operations on average. The follow up which was performed in a prospective study is now on average 19 months. In 11 of the 35 patients there was progressive or recurrent infection. In early infection the success rate was 78%, in late infection 38%.
This kind of therapy therefore can be used for salvage of infected hip implants and also can be applied in infected spine implants, knee implants or implants used in trauma surgery.