During Victoria's first pregnancy in 1840, in the first few months of the marriage, 18-year-old Edward Oxford attempted to assassinate her while she was riding in a carriage with Prince Albert on her way to visit her mother. Oxford fired twice, but either both bullets missed or, as he later claimed, the guns had no shot. He was tried for high treason, found not guilty by reason of insanity, committed to an insane asylum indefinitely, and later sent to live in Australia. In the immediate aftermath of the attack, Victoria's popularity soared, mitigating residual discontent over the Hastings affair and the bedchamber crisis. Her daughter, also named Victoria, was born on 21 November 1840. The Queen hated being pregnant, viewed breast-feeding with disgust, and thought newborn babies were ugly. Nevertheless, over the following seventeen years, she and Albert had a further eight children: Albert Edward (b. 1841), Alice (b. 1843), Alfred (b. 1844), Helena (b. 1846), Louise (b. 1848), Arthur (b. 1850), Leopold (b. 1853) and Beatrice (b. 1857).

Victoria's household was largely run by her childhood governess, Baroness Louise Lehzen from Hanover. Lehzen had been a formative influence on Victoria and had supported her against the Kensington System. Albert, however, thought that Lehzen was incompetent and that her mismanagement threatened his daughter's health. After a furious row between Victoria and Albert over the issue, Lehzen was pensioned off in 1842, and Victoria's close relationship with her ended.