Antidiuretic hormone (ADH) plays an essential part in the body's osmotic/fluid balance, sodium homeostasis, and blood pressure regulation. This hormone is synthesized in the hypothalamus and released from the posterior pituitary gland. In conditions such as Diabetes Insipidus (DI) and Syndrome of Inappropriate ADH (SIADH), there is a lack of synthesis or over-production of this hormone which results in negative downstream effects.

At the request of a podcast listener, we have decided to cover these conditions in this episode. Tune in as we discuss DI (central and nephrogenic), SIADH, and hypo/hypernatremia.

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