We're devoting this week's episode to the week of whiplash news about AstraZeneca's Covid-19 vaccine, subject of a baffling international incident with consequences still unfolding. First, we explain the series of late-night announcements that made global headlines. Then, our STAT colleague Helen Branswell joins us to discuss the implications for AstraZeneca, vaccine confidence, and the global effort to get doses in arms. Finally, STAT's Matthew Herper calls in to talk about Pascal Soriot, the hard-charging AstraZeneca CEO whose previously feted boldness might have backfired when it came to Covid-19.