Comedian/actor/writer Robin Ince (@robinince) and physicist/host/musician Brian Cox (@ProfBrianCox), both of BBC Radio's The Infinite Monkey Cage, were kind enough to sit down with Matt and Jesse while they were stateside for a recent live performance, discussing David Lynch's America, why the queen is common, Alzheimer's being treated by ultrasound, Brian's pop group D:Ream, the silliness of What The Bleep Do We Know!?, NPR's survey of great podcast episodes, The EPR Paradox, manifest causality in quantum field theory, the Large Hadron Collider reboot, Brian's upcoming BBC television show Forces of Nature, being wrongfully accused of arson, Andy's obsession with The Jinx and The Staircase, getting to perform with Eric Idle and ELO's Jeff Lynne and Andy's anger about the success of the Matt and Jesse episode.