First, we discuss a sudden spike of FDA rejections, which has resurfaced a time-honored frustration: You can’t always trust biotech companies to be honest about their conversations with the agency. Then, STAT's Lev Facher joins us to share his reporting from Louisiana, where a surge of Covid-19 deaths among the unvaccinated is having devastating effects on health workers. Before that, we talk about a curious case of alleged insider trading, medical conferences in the time of Delta, and the global vaccine push.