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Episode 29 - How Stress, Genes, and Environment Shape MCAS
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What if your body isn’t broken, but brilliant at surviving—and ready to learn safety? We unpack how epigenetics and nervous system regulation shape MCAS and histamine intolerance, showing why genes are not destiny and how daily choices flip the switches that guide inflammation and immune tone.
We start by reframing the “Is MCAS genetic?” question. While rare mast cell diseases can be mutation-driven, most MCAS looks multifactorial: inherited tendencies meet environment, stress load, sleep disruption, food quality, and toxin exposure. Teresa shares family history and career stress that map a lineage of bracing and hypervigilance—useful for survival, costly for regulation. From there, we make epigenetics practical: if genes are the blueprint, epigenetic marks are the volume knobs, turning pathways up or down based on signals like circadian rhythm, blood sugar stability, connection, and true rest.
Then we zoom into the biology. Mast cells sit at the intersection of immune and nervous systems, listening to cortisol, adrenaline, and neural cues. When the nervous system stays on high alert, mast cells often follow, fueling flushing, hives, GI distress, and tachycardia. That doesn’t reduce symptoms to “just stress.” It validates them while revealing leverage points: steady sleep and light exposure to calm circadian noise, protein-anchored meals to smooth glucose swings, gentle movement to support lymph and resilience, simplifying products to lower environmental load, and relational safety plus breath practices to teach a braced system to stand down.
The result is a hopeful, actionable path from survival to regulation. No silver bullets, no shame—just consistent signals that nudge inflammation lower and rebuild trust with your body. If you’re ready to live well with histamine intolerance rather than chase every trigger, this conversation offers both science and steps you can start today.
Want support applying this in real life? Subscribe, share with someone who needs hope, and leave a review to help others find the show. To work with Teresa, visit histaminehealthcoach.com or email [email protected] with the word “ready.”
I’m currently looking for five women who are ready to stop just managing histamine intolerance and start living well with it over the next 12 weeks. This is for women who feel like their bodies dictate their lives — women who are tired of reacting, restricting, and second-guessing. Women looking for relief, steadier routines, and the kind of confidence that leads to actually living well with histamine intolerance. If that’s you, email me at [email protected] with the word READY, and I’ll personally follow up so we can talk about what support might look like for you.
Follow me on Instagram
Follow me on Facebook
Email: [email protected]
Website: https://histaminehealthcoach.com
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By Teresa ChristensenSend a text
What if your body isn’t broken, but brilliant at surviving—and ready to learn safety? We unpack how epigenetics and nervous system regulation shape MCAS and histamine intolerance, showing why genes are not destiny and how daily choices flip the switches that guide inflammation and immune tone.
We start by reframing the “Is MCAS genetic?” question. While rare mast cell diseases can be mutation-driven, most MCAS looks multifactorial: inherited tendencies meet environment, stress load, sleep disruption, food quality, and toxin exposure. Teresa shares family history and career stress that map a lineage of bracing and hypervigilance—useful for survival, costly for regulation. From there, we make epigenetics practical: if genes are the blueprint, epigenetic marks are the volume knobs, turning pathways up or down based on signals like circadian rhythm, blood sugar stability, connection, and true rest.
Then we zoom into the biology. Mast cells sit at the intersection of immune and nervous systems, listening to cortisol, adrenaline, and neural cues. When the nervous system stays on high alert, mast cells often follow, fueling flushing, hives, GI distress, and tachycardia. That doesn’t reduce symptoms to “just stress.” It validates them while revealing leverage points: steady sleep and light exposure to calm circadian noise, protein-anchored meals to smooth glucose swings, gentle movement to support lymph and resilience, simplifying products to lower environmental load, and relational safety plus breath practices to teach a braced system to stand down.
The result is a hopeful, actionable path from survival to regulation. No silver bullets, no shame—just consistent signals that nudge inflammation lower and rebuild trust with your body. If you’re ready to live well with histamine intolerance rather than chase every trigger, this conversation offers both science and steps you can start today.
Want support applying this in real life? Subscribe, share with someone who needs hope, and leave a review to help others find the show. To work with Teresa, visit histaminehealthcoach.com or email [email protected] with the word “ready.”
I’m currently looking for five women who are ready to stop just managing histamine intolerance and start living well with it over the next 12 weeks. This is for women who feel like their bodies dictate their lives — women who are tired of reacting, restricting, and second-guessing. Women looking for relief, steadier routines, and the kind of confidence that leads to actually living well with histamine intolerance. If that’s you, email me at [email protected] with the word READY, and I’ll personally follow up so we can talk about what support might look like for you.
Follow me on Instagram
Follow me on Facebook
Email: [email protected]
Website: https://histaminehealthcoach.com