Comedian Carmen Morales (@TheFunnyCarmen) joins Andy, Jesse and Matt to talk about Matt's chipped tooth, the pros and cons of home dentistry, a nuclear fusion record, CRISPR and HIV, Andy's friend's Pioneertown-to-Big Bear breakdown, a million mice eating seabirds alive, letdowns from CBD, Carmen on HBO, updates from the Large Hadron Collider and our live event To 29 and Beyond, taking place June 7th and 8th.