Across the United States, record quantities of corn and soybeans have been harvested in recent years. However, according Dr. David Gustafson of the International Life Sciences Institute Research Foundation, this trend may soon change. The combined and uncertain effects of climate change could have a devastating impact on grain yields in the US Midwest, with major global implications for food security. To address these rising threats, Dr. Gustafson and his colleagues propose a new, coordinated network of field research sites at which precise data on the performance of current and future crops, cropping systems, and farm-level management practices in the US Midwest could be gathered. Dr. Gustafson joins us to describe the plan.