In this conversation, Jeremy, Andrew, and Brian discuss the Great Commission and its importance in the mission of the church. They define the Great Commission as the command given by Jesus to make disciples of all nations, baptizing them and teaching them to observe everything He commanded. They argue that the Great Commission should be the primary mission of the church because it is what Jesus Himself passed on to His disciples. They emphasize the connection between Jesus and His bride, the church, and how fulfilling the Great Commission is an act of love for lost humanity. They also discuss practical ways to fulfill the Great Commission on a local church level, such as evangelism, teaching, and supporting missionaries.