In today's episode find an analysis of creatine's multifaceted health benefits beyond athletic performance.

References:

-Paper #1: Prokopidis K, Giannos P, Triantafyllidis KK, Kechagias KS, Forbes SC, Candow DG. Effects of creatine supplementation on memory in healthy individuals: a systematic review and meta-analysis of randomized controlled trials. Nutrition Reviews. 2023 Apr 1;81(4):416-27.

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9999677/

-Paper #2: Forbes SC, Cordingley DM, Cornish SM, Gualano B, Roschel H, Ostojic SM, Rawson ES, Roy BD, Prokopidis K, Giannos P, Candow DG. Effects of creatine supplementation on brain function and health. Nutrients. 2022 Feb 22;14(5):921.

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8912287/

Comparative analysis of Time-Restricted Eating: a deep dive into metabolic outcomes and statistical indicators.

Three recent studies offer a comprehensive view into the effects

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References: 

-Paper #1. Wilkinson MJ, Manoogian EN, Zadourian A, Lo H, Fakhouri S, Shoghi A, Wang X, Fleischer JG, Navlakha S, Panda S, Taub PR. Ten-hour time-restricted eating reduces weight, blood pressure, and atherogenic lipids in patients with metabolic syndrome. Cell metabolism. 2020 Jan 7;31(1):92-104.

Link:https://www.cell.com/cell-metabolism/fulltext/S1550-4131(19)30611-4?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS1550413119306114%3Fshowall%3Dtrue

-Paper #2. Lowe DA, Wu N, Rohdin-Bibby L, Moore AH, Kelly N, Liu YE, Philip E, Vittinghoff E, Heymsfield SB, Olgin JE, Shepherd JA. Effects of time-restricted eating on weight loss and other metabolic parameters in women and men with overweight and obesity: the TREAT randomized clinical trial. JAMA internal medicine. 2020 Nov 1;180(11):1491-9.

Link:https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2771095

-Paper #3. Jamshed H, Steger FL, Bryan DR, Richman JS, Warriner AH, Hanick CJ, Martin CK, Salvy SJ, Peterson CM. Effectiveness of early time-restricted eating for weight loss, fat loss, and cardiometabolic health in adults with obesity: a randomized clinical trial. JAMA internal medicine. 2022 Sep 1;182(9):953-62.

Link: https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2794819

In this episode find a triptych analysis on cannabis use disorder and surgical outcomes.

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References:

- Paper #1. Potnuru PP, Jonna S, Williams GW. Cannabis Use Disorder and Perioperative Complications. JAMA surgery. 2023 Jul 5.

Link: https://jamanetwork.com/journals/jamasurgery/article-abstract/2806774

- Paper #2. Chiu RG, Patel S, Siddiqui N, Nunna RS, Mehta AI. Cannabis abuse and perioperative complications following inpatient spine surgery in the United States. Spine. 2021 Jun 1;46(11):734-43.

Link:https://journals.lww.com/spinejournal/abstract/2021/06010/cannabis_abuse_and_perioperative_complications.9.aspx

- Paper #3. Goel A, McGuinness B, Jivraj NK, Wijeysundera DN, Mittleman MA, Bateman BT, Clarke H, Kotra LP, Ladha KS. Cannabis use disorder and perioperative outcomes in major elective surgeries: a retrospective cohort analysis. Anesthesiology. 2020 Apr 1;132(4):625-35.

Link: https://pubs.asahq.org/anesthesiology/article/132/4/625/108922/Cannabis-Use-Disorder-and-Perioperative-Outcomes

In this episode we talk about the possible correlation between sleep and obesity in children. Summary based on the paper of Mei H, Jiang F, Li L, Griswold M, Liu S and Mosley T, published on the Journal of human genetics in 2020.

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Reference: Study of genetic correlation between children’s sleep and obesity. Mei H, Jiang F, Li L, Griswold M, Liu S, Mosley T. Journal of human genetics. 2020 Nov;65(11):949-59.

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048051/

In this episode you will find an executive summary on the health implications of chronotypes and night shift work.

We summarize the analysis of three papers concerning the metabolic effect of night shifts published in Annals of Internal Medicine in 2023, PLOS One in 2021, and BMC Diabetology and Metabolic Syndrome in 2020.

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References:

-Paper #1: Kianersi S, Liu Y, Guasch-Ferré M, Redline S, Schernhammer E, Sun Q, Huang T. Chronotype, Unhealthy Lifestyle, and Diabetes Risk in Middle-Aged US Women: A Prospective Cohort Study. Annals of Internal Medicine. 2023 Sep 12.

Link: https://www.acpjournals.org/doi/10.7326/M23-0728?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed

-Paper #2: Cheng WJ, Liu CS, Hu KC, Cheng YF, Karhula K, Härmä M. Night shift work and the risk of metabolic syndrome: Findings from an 8-year hospital cohort. Plos one. 2021 Dec 13;16(12):e0261349.

Link: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0261349

-Paper #3: Brum MC, Dantas Filho FF, Schnorr CC, Bertoletti OA, Bottega GB, da Costa Rodrigues T. Night shift work, short sleep and obesity. Diabetology & metabolic syndrome. 2020 Dec;12:1-9.

Link: https://dmsjournal.biomedcentral.com/articles/10.1186/s13098-020-0524-9

In this episode, you will find a comparative analysis of observational, meta-analytic, and trial-based evidence on proton pump inhibitors and the risk of dementia.

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References:

-Paper #1: Zhang P, Li Z, Chen P, Zhang A, Zeng Y, Zhang X, Huang Q, Liu D, Qi S, Mao C. Regular proton pump inhibitor use and incident dementia: population-based cohort study. BMC medicine. 2022 Sep 1;20(1):271.

Link: https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-022-02478-y

-Paper #2: Caetano C, Veloso M, Borda S. Proton pump inhibitors and dementia: what association? Dementia & Neuropsychologia. 2023;17.

Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10229084/

-Paper #3: Mehta RS, Kochar B, Zhou Z, Broder JC, Chung P, Yang K, Lockery J, Fravel M, Ryan J, Mahady S, Orchard SG. Association of Proton Pump Inhibitor Use With Incident Dementia and Cognitive Decline in Older Adults: A Prospective Cohort Study. Gastroenterology. 2023 Sep 1;165(3):564-72.

Link: https://www.gastrojournal.org/article/S0016-5085(23)00873-9/fulltext?referrer=https%3A%2F%2Fpubmed.ncbi.nlm.nih.gov%2F

In this episode find a comparative analysis of three studies on semaglutide for weight loss and recommendations for clinical practice. This comparative analysis evaluates three key studies on the use of semaglutide for weight loss. Each study examined the efficacy and safety of semaglutide.

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References:

-Paper #1: Ghusn W, De la Rosa A, Sacoto D, Cifuentes L, Campos A, Feris F, Hurtado MD, Acosta A. Weight loss outcomes associated with semaglutide treatment for patients with overweight or obesity. JAMA Network Open. 2022 Sep 1;5(9):e2231982-.

Link: https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2796491

-Paper #2: Wilding JP, Batterham RL, Calanna S, Davies M, Van Gaal LF, Lingvay I, McGowan BM, Rosenstock J, Tran MT, Wadden TA, Wharton S. Once-weekly semaglutide in adults with overweight or obesity. New England Journal of Medicine. 2021 Mar 18;384(11):989-1002.

Link: https://pubmed.ncbi.nlm.nih.gov/33567185/

-Paper #3: Gao X, Hua X, Wang X, Xu W, Zhang Y, Shi C, Gu M. Efficacy and safety of semaglutide on weight loss in obese or overweight patients without diabetes: a systematic review and meta-analysis of randomized controlled trials. Frontiers in pharmacology. 2022 Sep 14;13:935823.

Link: https://www.frontiersin.org/articles/10.3389/fphar.2022.935823/full

In this episode find a comparative analysis of Type 2 Diabetes Mellitus and Alzheimer's disease connections.

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References:

1. Michailidis M, Moraitou D, Tata DA, Kalinderi K, Papamitsou T, Papaliagkas V. Alzheimer’s disease as type 3 diabetes: common pathophysiological mechanisms between Alzheimer’s disease and type 2 diabetes. International Journal of Molecular Sciences. 2022 Feb 28;23(5):2687.

Link: https://www.mdpi.com/1422-0067/23/5/2687

2. Tang B, Wang Y, Jiang X, Thambisetty M, Ferrucci L, Johnell K, Hägg S. Genetic variation in targets of antidiabetic drugs and Alzheimer disease risk: a Mendelian randomization study. Neurology. 2022 Aug 16;99(7):e650-9.

Link: https://n.neurology.org/content/99/7/e650.long

3. Moran C, Beare R, Wang W, Callisaya M, Srikanth V, Alzheimer's Disease Neuroimaging Initiative (ADNI. Type 2 diabetes mellitus, brain atrophy, and cognitive decline. Neurology. 2019 Feb 19;92(8):e823-30.

Link: https://n.neurology.org/content/92/8/e823.long

Welcome to "Espresso Knowledge Shots," a podcast by Agora Project, your go-to podcast for quick and easy-to-digest summaries and analyses of research papers across a wide range of medical topics and other health-related fields.

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