Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+

Today, I am delighted to reconnect with Dr. Darren Candow.

Dr. Candow is a distinguished professor and an internationally renowned researcher on creatine monohydrate, nutrition, and physical activity who joined me before on Episode 301, where we spoke about creatine. 

We are doing an AMA session today, delving into various themes surrounding creatine, from debunking outdated RDA recommendations to exploring the combined effects of strength training and creatine efficacy. We look into the cognitive benefits of creatine, exploring how it interacts with caffeine and its implications for bone health, hydration, anabolic resistance, and metabolic health. 

I trust you will find today's AMA session as enlightening and enriching as I did while recording it.

IN THIS EPISODE YOU WILL LEARN:

Bio: Dr. Darren Candow

Dr. Darren Candow, PhD, CSEP-CEP, is Professor and Director of the Aging Muscle and Bone Health Laboratory in the Faculty of Kinesiology and Health Studies at the University of Regina, Canada. The overall objectives of Dr. Candow’s research program are to develop effective lifestyle interventions involving nutrition (primarily creatine monohydrate) and physical activity (resistance training) that are clinically and practically relevant for improving musculoskeletal aging and reducing the risk of falls and fractures. Dr. Candow has published over 120 peer-reviewed journal manuscripts, supervised over 20 MSc and PhD students, and received research funding from the Canadian Institutes of Health Research, Canada Foundation for Innovation, the Saskatchewan Health Research Foundation, the National Institute of Health, and the Nutricia Research Foundation. In addition, Dr. Candow serves on the editorial review boards for the Journal of the International Society of Sports Nutrition, Nutrients, and Frontiers.

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Previous Episode Mentioned:

⁠Ep. 301 Creatine: The Best Supplement for Better Bones & Brain Health with Darren Candow, PhD, CSEP-CEP⁠

Today, I’m honored to reconnect with Dr. Tommy Wood. He is a neuroscientist, a performance coach, and an elite-level professional nerd. He's also currently an associate professor of pediatrics and neuroscience at the University of Washington. He received his bachelor's in biochemistry from the University of Cambridge, a medical degree from the University of Oxford, and a PhD in physiology and neuroscience from the University of Oslo.

In our conversation, we discuss his new book, The Stimulated Mind, and he explains how dementia is a confluence of factors that accumulate over decades, important contributors to dementia, and ways we can help prevent it. We explore the concept of headroom, specific risk factors for neurocognitive decline, brain fog in midlife, the 10-year HRT timing window, and the evidence supporting these concepts. Dr. Tommy shares what we can learn from his work with elite-level athletes, along with some of the biggest misconceptions in the brain health space, and his 3s model of stimulation, sleep, and nutrient supply. He also explains why nutritional status matters for neurocognitive function.

Stay tuned for today’s insightful conversation with Dr. Tommy Wood. I loved his new book, The Stimulated Mind, and it will definitely be part of my must-reads for 2026!

IN THIS EPISODE, YOU WILL LEARN:

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I’m delighted to reconnect with my dear friend Ben Azadi today, in honor of his newly revised book, Keto Flex.

Ben is a leading authority on metabolic health, an international Keystone speaker, and the New York Times best-selling author of Metabolic Freedom.

In today’s conversation, we discuss why women fail on keto. We examine how women’s menstrual cycles and various life stages influence both the ketogenic diet and intermittent fasting, and the importance of coming out of ketosis and incorporating feast days. We explain what the Randall cycle is, why we need to be finely tuned to it, how to support healthy cortisol regulation, particularly the HPA axis, and tools to determine whether we are balanced within the autonomic nervous system, including heart rate variability, sleep, and whether our glucose and ketones are within range. We also explore the effects of anti-nutrients and elimination diets, and Ben shares his approach for women who feel keto hasn't worked for them, explaining why keto should be viewed as a process rather than a diet.

This is, as always, a truly invaluable conversation with my dear friend Ben Azadi. Stay tuned, as we will also be offering giveaways to listeners of Ben's new book, Keto Flex.

IN THIS EPISODE, YOU WILL LEARN:

Bio: Ben Azadi

Ben Azadi, FDN-P, is a leading authority on metabolic health, an international keynote speaker, and the New York Times bestselling author of Metabolic Freedom.

After facing his own health challenges, Ben transformed his life in 2008—losing 80 pounds and stepping into metabolic freedom. That turning point sparked a global mission: to help 1 billion people break free from physical and mental obesity through education, not medication.

With 18+ years in the health and wellness space, Ben is now leading a bold 10-year initiative to naturally reverse type 2 diabetes in 1 million people.

Through his work, Ben has reached millions worldwide and personally coached thousands to reclaim their health. His audience includes nearly 3M+ on digital platforms, more than 1M YouTube subscribers with over 100M views, and his top-ranked podcast, The Ben Azadi Show, which has surpassed 100 million downloads.

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I am thrilled to connect with my friend and colleague, Dr. Anthony Youn today. 

Dr. Youn is a nationally recognized board-certified plastic surgeon and the author of many best-selling books. He has a massive social media presence and hosts the widely acclaimed podcast The Holistic Plastic Surgery Show.

In our conversation today, we dive into Dr. Youn’s new book, Younger for Life, and he offers valuable insights on skin health and overall well-being. We explore the aging process and address oxidative-free radical damage, chronic inflammation, autophagy, and the impact of processed foods. We also get into helpful supplements for skin support, examine the concept of greenwashing, and discuss sunscreen, exfoliation, in-office treatments, breast implant illness, and the power of lifestyle choices.

Stay tuned for more!

IN THIS EPISODE YOU WILL LEARN:

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I am honored to connect with Dr. Sharon Stills today. She is a graduate of naturopathic medical school with extensive training in European biological medicine, bioidentical hormone replacement, and anti-aging therapies.

In our conversation today, we explore terrain-based medicine and strategies to support women in perimenopause and beyond. We talk extensively about gut health, the estroblome, the microbiome, how European biological medicine views these as terrain, disruptive factors, and why they matter for women in midlife. We also examine the influence of the lymphatic system and how castor oil packs support it, bioidentical hormones as a lifelong tool rather than a temporary fix, and why menopause is a sacred second act in women's lives.

Dr. Stills is thoughtful, insightful, and grounded, and I know you will enjoy this conversation with her as much as I did recording it.

IN THIS EPISODE, YOU WILL LEARN:

Bio: Dr. Sharon Stills

Dr. Sharon Stills, a licensed Naturopathic Medical Doctor and graduate of The Sonoran University (2001), has spent over two decades transforming women’s health, with a special focus on guiding women through perimenopause and menopause.

Creator of the pioneering RED Hot Sexy Meno(pause) Program and host of the annual Mastering Your Meno(pause) Transition summit, she combines her expertise in European Biological Medicine, pro-aging therapies, and Bio-identical Hormone Replacement to help women rediscover vitality with natural methods.

A respected voice in her field, Dr. Stills has lectured internationally at the Paracelsus Academy in Switzerland, contributed to Women’s Health Network, and served on the boards of the Bio-Regulatory Medicine Institute and UCLA’s Archive of Healing.

She recently opened the Lasting Wellness Center in Scottsdale, AZ—alongside her son, Dr. Ben Stills—offering advanced diagnostic and therapeutic care for chronic illness and women’s health.

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Welcome to the latest Midlife Minute episode.

Today, we’re talking about elimination diets, iron, and ferritin. I share my personal experience with prolonged antibiotic and antifungal use, clarify what the research actually says about restrictive diets, nutrient deficiencies, fatigue, and brain fog, and highlight why it’s essential to understand your iron status during the menopausal transition.

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Links:

1. The Importance of Nutrition in Menopause and Perimenopause—A Review

2. Weight gain during the menopause transition: Evidence for a mechanism

dependent on protein leverage

3. The gut microbiota in menopause: Is there a role for prebiotic and probiotic

solutions?

4. Cognitive Performance in Relation to Systemic and Brain Iron at Perimenopause

5. Accelerated Increase in Ferritin Levels During Menopausal Transition as a Marker of Metabolic Health

6. Iron and Menopause: Does Increased Iron Affect the Health of Postmenopausal Women?

7. Iron deficiency in peri-menopausal women: Clinical considerations from an expert consensus

8. Cognitive Function in Peri- and Postmenopausal Women: Implications for

Considering Iron Supplementation

I’m delighted to reconnect with Dr. Philip Ovadia today. He is a board-certified cardiothoracic surgeon with over 20 years of experience in the operating room and the founder of Ovadia Heart Health, a telemedicine practice focused on preventing and treating metabolic and cardiovascular disease through dietary and lifestyle intervention. He has co-authored two books, including, most recently, Stay Off My Kitchen Table.

Today we discuss key statistics on metabolic health, metabolic health challenges, and lifestyle interventions, including Dr. Ovadia’s three I's (insulin resistance, inflammation, and imaging), optimal lab values, vulnerable populations, and why prevention is key, especially for women and heart disease. We discuss the influence of gut and metabolic health, elimination diets, the reintroduction of food, and the positive influence of AI on medicine. We also cover the impact of GLP-1s and so much more.

Stay tuned for an insightful conversation with Dr. Phil Ovadia on why improving metabolic health is one of the most important steps you can take to prevent cardiovascular disease.

IN THIS EPISODE, YOU WILL LEARN:

Bio: Dr. Philip Ovadia

Conducting over 3,000 heart surgeries taught Dr. Philip Ovadia that good health comes from lifestyle and nutrition, not surgery. Sadly, many of his patients considered their heart attacks “inevitable.”

Having lost 100lbs to overcome lifelong obesity, Dr Ovadia is on a mission to help people stay off his operating table by teaching them how to never need a heart surgeon through his Telehealth practice, Ovadia Heart Health.

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Today, we have a sponsored episode featuring One Skin, a super high-value company I’ve worked with over the past two years.

I'm joined today by Dr. Carolina Reis Oliveira, one of the CEOs and co-founders of One Skin. Dr. Oliveira holds a PhD in stem cell biology and tissue engineering. She has co-invented five patents and co-authored numerous scientific publications. She and her team are disrupting the outdated anti-aging skincare industry with their cutting-edge research on skin and longevity.

In our conversation, Dr. Reis Oliveira shares her journey from receiving her PhD to co-founding One Skin. We explore the impact of cellular senescence and immunosenescence and how estrogen receptors in the skin change during perimenopause and menopause, increasing the rate of senescent cell accumulation. We discuss skin as a longevity organ and the research behind the OS-01 peptide, including how it supports the microbiome and blood flow, its exceptional results for increasing hair thickness, and how to use this peptide in skin, body, or hair care. We also cover the effects of sun and environmental exposures on skin aging, and Dr. Reis Oliveira discusses her current research on the influence of GLP-1s on stem cells and skin health.

Stay tuned for a truly interesting and insightful conversation on the science of skin, longevity, and the latest research behind One Skin.

IN THIS EPISODE, YOU WILL LEARN:

Bio: Dr. Carolina Reis Oliveira

Dr. Carolina Reis Oliveira is the CEO and co-founder of One Skin. She holds a Ph.D. in stem cell biology and tissue engineering, is a co-inventor of 5 patents, and a co-author of numerous scientific publications. She relocated from Brazil to Silicon Valley in 2016 to found One Skin, a fast-growing longevity company developing products to promote skin age reversal by targeting a central driver of aging, the accumulation of senescent cells.

Carolina and her team are disrupting the outdated anti-aging skincare industry with their groundbreaking research around skin and longevity.

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I am honored to have Dr. Carrie Jones back on the podcast today. She’s a naturopathic physician and hormone expert with over 20 years of clinical experience in women's health and endocrinology.

In today’s conversation, we unpack common social media myths about midlife, the influence of lifestyle choices in perimenopause, the role of cortisol and hormones, and current research on the parasympathetic nervous system. Dr. Jones explains vagal freeze, how our stress response can exacerbate it, and why stress has become so normalized. We also explore the influence of synthetic hormones, thyroid propaganda, immune system function, autoimmunity, lab reference values and ranges, and the timing hypothesis of hormone replacement therapy, and Dr. Jones shares her favorite new supplements.

Stay tuned for another insightful conversation with one of my favorite voices in the hormone space.

IN THIS EPISODE, YOU WILL LEARN:

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I’m excited to welcome Dr. Dave Rabin today. Dr. Rabin is a translational neuroscientist and board-certified psychiatrist who specializes in treatment-resistant PTSD, addiction, vagus nerve activation, and HRV as a biomarker. He is also the author of A Simple Guide to Being Alive, a thoughtful and helpful guide to supporting our health, and one of my favorite books in the last several years.

In this episode, we explore the habitat crisis and why we cannot bully our nervous system into safety. Dr. Rabin explains trauma and support, healing from within, the role of anhedonia, and why the absence of pleasure is a physiologic issue rather than a moral one. We also discuss wonder, awe, and play; the importance of touch, intimacy, eye contact, oxytocin, and co-regulation; the role of psychedelics, medication, and psychotherapy in trauma healing, and how kindness toward ourselves and others can help activate the vagus nerve.

Stay tuned for an insightful discussion on supporting your nervous system, healing from within, and rethinking what it means to be truly alive.

IN THIS EPISODE, YOU WILL LEARN:

Bio: Dr. Davis Rabin

Dr. David M. L. Rabin, MD, PhD, is a translational neuroscientist, psychiatrist, entrepreneur & inventor on a mission to cure mental illness. He has been studying the impact of chronic stress in humans for over 20 years, focusing on trauma, addiction, and human performance. Dr. Rabin is a Senior Research Scientist at the Institute for Human and Machine Cognition, the Chief Medical Officer and co-founder at Apollo Neuroscience, the Executive Director of The Board of Medicine Nonprofit Medical Board, and the Medical Director of The Apollo Clinic. In addition to hosting The Psychedelic Report and Your Brain Explained podcasts, Dr. Rabin regularly serves as an expert for news outlets such as The New York Times, Vogue, CBS News, The Washington Post, and The Wall Street Journal. In his spare time, he enjoys cooking, dancing, playing volleyball, sailing, and hiking with his wife, Kathryn, and their son, Sammy.

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