The provided sources explore diverse aspects of hormonal influences and potential interventions in various health conditions. One study investigates the impact of **3,3′-diindolylmethane (DIM)** on estrogen metabolism in patients with thyroid proliferative disease. Another examines the effectiveness of a **proprietary blend of pomegranate and cocoa extracts** in alleviating symptoms of aging in males, focusing on perceived stress and safety parameters. Several sources discuss **testosterone levels in men**, including the effects of aging and exercise, and the potential of **aromatase inhibition** to restore these levels in older men with hypogonadism. Lastly, one article reviews the role of **black pepper extract (Bioperine®)** as a bioavailability enhancer for iron supplementation, particularly in physically active individuals, to combat iron deficiency and improve athletic performance.

Various Factors May Modulate the Effect of Exercise on Testosterone Levels in Men

Endogenous transient doping: physical exercise acutely increases testosterone levels-results from a meta-analysis

Aromatase inhibitors in men: effects and therapeutic options

Testosterone vs. aromatase inhibitor in older men with low testosterone: effects on cardiometabolic parameters

Effects of aromatase inhibition in elderly men with low or borderline-low serum testosterone levels

Aromatase inhibition restores testosterone levels in hypogonadal older men

Structural and Functional Characterization of Aromatase, Estrogen Receptor, and Their Genes in Endocrine-Responsive and – Resistant Breast Cancer Cells

Testosterone and Sarcopenia

Aromatase Inhibitors in Erectile Dysfunction

Sleep, Rhythms, and the Endocrine Brain: Influence of Sex and Gonadal Hormones

https://www.ncbi.nlm.nih.gov/…articles/PMC6987613/

https://eje.bioscientifica.co…ls/eje/169/5/705.xml

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897047/

https://pubmed.ncbi.nlm.nih.gov/24928451/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2805471/

https://www.ncbi.nlm.nih.gov/books/NBK92772/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975356/

https://pubmed.ncbi.nlm.nih.gov/1901550/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287254/

https://pubmed.ncbi.nlm.nih.gov/10442580/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667256/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1476110/

https://www.medsci.org/v19p1290.htm

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048776/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3073592/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353321/