Framatube

Erklärvideo zur Veröffentlichung:

Laura Schaedel, Charlotta Lorenz, Anna V. Schepers, Stefan Klumpp, Sarah Köster: Nature Communications (2021)

Vimentin intermediate filaments stabilize dynamic

The cytoskeleton determines cell mechanics and lies at the heart of important cellular functions. Growing evidence suggests that the manifold tasks of the cytoskeleton rely on the interactions between its filamentous components—actin filaments, intermediate filaments, and microtubules. However, the nature of these interactions and their impact on cytoskeletal dynamics are largely unknown. Here, we show in a reconstituted in vitro system that vimentin intermediate filaments stabilize microtubules against depolymerization and support microtubule rescue. To understand these stabilizing effects, we directly measure the interaction forces between individual microtubules and vimentin filaments. Combined with numerical simulations, our observations provide detailed insight into the physical nature of the interactions and how they affect microtubule dynamics. Thus, we describe an additional, direct mechanism by which cells establish the fundamental cross talk of cytoskeletal components alongside linker proteins. Moreover, we suggest a strategy to estimate the binding energy of tubulin dimers within the microtubule lattice.

Publikation: https://doi.org/10.1038/s41467-021-23523-z

In diesem Video erklären wir eins unserer Experimente am Europäischen Freie-Elektronen-Laser EuXFEL in Schenefeld zur Dynamik explodierender Plasma-Blasen in Wasser (englische Tonspur + Untertitel, jetzt auch deutsche LLM-Übersetzung).

Publikation dazu: https://www.nature.com/articles/s41467-021-23664-1

Let's visit Louisiana in the newest DLC of „American Truck Simulator“. Of course I'm using again the head tracking tool „LookPilot”.

I play on Linux Mint 22.2, with LookPilot natively and American Truck Simulator via Proton 10.0-3. Even though the game supports Linux natively, the head tracking wouldn't work that way, unfortunately.

American Truck Simulator: https://store.steampowered.com/app/270880

Freightliner Fifth Generation Cascadia Walk-Around: https://blog.scssoft.com/2024/10/scs-on-road-freightliner-fifth.html

LookPilot: https://store.steampowered.com/app/3326890 / https://lookpilot.app/

My website: https://hatnix.net

In this special live episode from the Software Architecture Gathering, Clare Sudbery joins Eberhard for an open conversation about learning, empathy, and psychological safety in tech. Building on her talk “Let’s Stop Making Each Other Feel Stupid”, Clare reflects on how the culture of expertise in software development can unintentionally discourage curiosity and collaboration. Together, they explore practical ways to create environments where questions are welcomed, mistakes become opportunities for growth, and knowledge sharing thrives behind the scenes of architecture and development.

Links from Clare’s talk

(aka Marisa's teambomb) Her bonus spellcard in Touhou 8: Imperishable Night (on Normal difficulty). Pretty much the same width, but more mobile than her Hard/Lunatic counterparts.

Mystia's second spellcard in Touhou 8: Imperishable Night (on the Hard difficulty). Not much to say about it but getting up-close to shotgun the boss becomes progressively more tricky the higher the difficulty you go.

Shot used: Youmu + Yuyuko

Das Video zeigt einige Bilder von meiner Japan Reise im Jahr 2024.

Aujourd'hui on va parler de métrologie : une des choses les plus importantes qui sert de base à tout : science, commerce, industrie, etc.

Vidéo en partenariat avec le LNE à l’occasion des 150ans du mètre : https://www.lne.fr/fr

💕 Soutenir la chaîne sur Tipeee : https://fr.tipeee.com/monsieur-bidouille

📸 Instagram : https://www.instagram.com/mrbidouille/

✍🏻 Bluesky : https://bsky.app/profile/monsieurbidouille.fr

Ma chaîne : https://www.youtube.com/user/monsieurbidouille

#métrologie #mètre #reportage

Diese Folge hat nicht wirklich viel mit Pentax zu tun. Es zeigt die Krimmler Wasserfälle und die Berglandschaft in deren Umgebung.