This week, the gang is joined by Dr. Amy Kruse, Chief Investment Officer of Satori Neuro, where she reveals her philosophy around neurotechnology investing and how aspiring scientists can best position themselves for the bright future ahead.

This week, the gang heads out west with Pengfei Song, Associate Professor at Duke University. They get into functional ultrasound brain imaging, the implications of vascular microbubbles, shear wave neuromodulation possibilities, and next generation brain computer interfaces.

Follow the FUS busters on their epic journey to untangle the origins of the double pulse repetition frequency. Be warned, you may not like what you find!

This week we join Dr. Samuel Pichardo to discuss pushing acoustic simulations to the limit with plans for BabelBrain 1.0, how essential tremor is n his crosshairs, and how electrical fields can steer the focus of a single element transducer.

Lived experience and mental health advocate Jon Nelson brings the reality of mental health front and center, from deep brain stimulation to an even deeper stigmatization.

Not the first, and definitely not the last time the gang discusses the growing prevalence of self experimentation as FUS gets wind in its sails. Listen in on thoughts around barrier to entry, a viral twitter post, chasing ghosts, and vagus nerve modulation.

This week Elly Martin, Associate Professor of University College London, joins the squad to talk about cryogenic ultrasonic unfreezing of living tissue, UCL's brain wide hemispheric interface, and the art of metrology.

Noah Philip, Professor at Brown University joins the pack to discuss what's been going on inside one of the most secretive efforts in focused ultrasound neuromodulation. This episode covers new findings his work with amygdala stimulation in PTSD, the honors of working with veterans, how old stim habits die hard, and some hot takes on wellness devices gone clinical.

This week Raag Airan joins the crew to change the way we think about ultrasound interactions with the brain. Follow along as we chat about using ultrasound to locally release drugs, clearing metabolites and particulates for stroke and dementia, and how he thinks about tradeoffs between exploration and scientific rigor. Check out Raags latest (FUS) win below

https://www.nature.com/articles/s41587-025-02866-8

Charles and Keith discuss the recent serious adverse event and what it means for the field