GameChangers

Most prescribers believe that short course of steroids have no serious adverse effects, but a recent study from the Annals of Internal Medicine challenges that notion.  What does the pharmacist need to know about the short and long term adverse effects of steroids and how to proactively prevent them?

Additional Resources/References

Association between Oral Corticosteroid Bursts and Severe Adverse Events: https://www.acpjournals.org/doi/pdf/10.7326/M20-0432 

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Ethanol use disorder continues to be a major problem in the U.S.  The stress and anxiety related to the COVID-19 pandemic may exacerbate alcohol use disorder. Tune in to this episode to learn the latest in guideline updates relative to the management of ethanol withdrawal.

Additional Resources/References

Alcohol Withdrawal Management Guideline: https://www.asam.org/Quality-Science/quality/guideline-on-alcohol-withdrawal-management

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Overinflamation or cytokine storm is said to be the driver of acute respiratory disorder disease (ARDS) in COVID patients.  

A recent study conducted in the United Kingdom suggests that the steroid dexamethasone may be a weapon for prevention.  In this episode, we discuss the study that caused the National Health Service in the U.K. and the CDC to change their recommendations for steroids and severe COVID.

Additional Resources/References

Ramdomised Evaluation of COVID-19 Therapy: https://www.recoverytrial.net/ 

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The COVID-19 pandemic has disproportionally affected Latinx Americans.  Learn how pharmacists can optimize patient care for Latinx patients by discussing how to overcome economic and language barriers.  In this episode, we'll talk with Dr. Sally Haack who cares for Latinx patients on a daily basis in her pharmacy practice.

Special guest:

Sally Haack, PharmD, BCPS Associate Professor Drake University

This episode is accredited for CPE.  

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Many patients over age 65 take daily medications that have anticholinergic properties. We know the addition of these drugs can affect quality of life and cognition.  In this episode, we talk with Dr. Kristin Meyer, an expert in geriatrics to  explore the latest data and discuss what Pharmacists can do to promote the appropriate use of anticholinergics.

Additional Resources/References

Beers Criteria:

By the 2019 American Geriatrics Society Beers Criteria® Update Expert Panel. American Geriatrics Society 2019 Updated AGS Beers Criteria® for Potentially Inappropriate Medication Use in Older Adults. J Am Geriatr Soc. 2019;67(4):674-694. doi:10.1111/jgs.15767

Anticholinergic Risk Scale:

Rudolph JL, Salow MJ, Angelini MC, McGlinchey RE. The Anticholinergic Risk Scale and Anticholinergic Adverse Effects in Older Persons. Arch Intern Med. 2008;168(5):508–513. doi:10.1001/archinternmed.2007.106

Recent arge study associating anticholinergics with dementia:

Coupland CAC, Hill T, Dening T, Morriss R, Moore M, Hippisley-Cox J. Anticholinergic Drug Exposure and the Risk of Dementia: A Nested Case-Control Study. JAMA Intern Med. 2019;179(8):1084–1093. doi:10.1001/jamainternmed.2019.0677

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The American College of Rheumatology recently published new guidelines for the treatment of Gout. While gout is well understood and the medications to treat gout are both effective and affordable, implementation of the new ARC guidelines will, ideally, lead to improved quality of care for patients with gout.  In this episode, Dr. Wall discusses guideline changes and important pearls so pharmacists may optimize medication therapy for patients suffering from gout.

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Racism is a public health emergency and a root cause of social determinants of health. If we are to practice patient-centered care, and education our pharmacists to better serve their patients, we ought to act to dismantle structural racism and start by having some honest conversations. In this episode, we'll talk with Dr. Vibhuti Arya about our role as pharmacists in addressing this public health emergency.

Special Guest: 

Vibhuti Arya, PharmD

Associate Clinical Professor, St. John's University

Clinical Advisor, New York City Department of Health and Mental Hygiene

View Dr. Arya's Tedx Talk here: https://www.youtube.com/watch?v=vnYE0n7Tx_o 

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Racism, SDOH, social determinants of health, anti-racist  

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Recently news suggests low vitamin D levels have been associated with increased risk of COVID-related morbidity and mortality. We know that vitamin D is a safe fat soluable vitamin that is difficult to "overdose" on.  What should the pharmacist know in terms of repletion dose and signs of toxicity? Since many patients do not get enough vitamin D in their diets, large medical societies and organizations recommend daily vitamin D for this reason.   This episode will focus not on the claims of efficacy of Vitamin D in COVID, but will instead discuss how your patients can replete vitamin D levels and the risks of toxicity in overrepletion.

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Recently, Remdesivir was given Emergency Use Authorization (EUA) status by the U.S. Food and Drug Administration (FDA) for use in COVID based on a heretofore unpublished study. The study, conducted by NIAID,  is the subject of this episode.

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Buprenorphine has been shown in numerous studies to be safe and effective in opioid use disorder, yet < 10% patients with Opioid Use Disorder receive drug treatment. In this episode, we discuss what the general pharmacist needs to know about the most powerful weapon we have for Opioid Use Disorder: buprenorphine

This episode is accredited for CPE.  This episode is accredited for CPE.  For CE details and to claim credit click here:  https://bit.ly/3dPEj0i 

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