GEN Podcasts

GEN Podcasts

By Genetic Engineering and Biotechnology NewsScienceTechnologyLife Sciences
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GEN Podcasts episodes

  • Find the Right Fit when Tackling Late Stage Bioprocessing Challenges
    Filtration, filtration, filtration! It’s one of the critical factors to instituting a successful biomanufacturing process and often the element that gives scientists and engineers the most difficulty. Late-stage bioprocesses often require large volume manufacturing to meet supply requirements, and these increased volumes create challenging filtration operations—disrupting facility fit. Because so much is at stake for companies to generate bioproducts in short timeframes, when faced with these types of bioproduction challenges, organizations will waste valuable time and resources on developing creative solutions, in addition to making undesirable capital purchases. In this GENcast, we explore different troubleshooting techniques that the M Lab™ Collaboration Center experts employed, together with Biogen, to solve their facility fit challenges.

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    11 min
  • Antibody Drug Conjugates: Manufacturing Precision Guided Therapeutics
    While the idea of a magic bullet that treats all maladies is a concept grounded in antiquity, antibody drug conjugates (ADCs) get a lot closer than almost any other class of drugs. The coupling of broadly cytotoxic compounds to the precision targeting of monoclonal antibodies creates a therapeutic weapon of disease destruction. Yet, as with most biotherapeutic manufacturing processes, scaling-up these compounds efficiently is never straight forward. Still, with the global ADC market proliferating, scientists and engineers are looking for the best path forward to address their bioprocessing challenges.In this GENcast, we hear from a panel of ADC experts about how they have addressed some of the most challenging aspects of manufacturing these complex therapeutics and how they are reading the current ADC manufacturing terrain.

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    15 min
  • Vaccinating the World One Collaboration at a Time
    Positive global health outcomes are often contingent on more than just great science, as knowledge sharing is also a fundamental part of achieving public health goals. With drug resistance on the rise for many pathogens once thought well managed clinically, scientists are looking toward the development of new vaccines to help reduce morbidity and mortality for many global diseases. Collaboration between academia, industry, suppliers, and government organizations is crucial for the successful development of these vaccines, as these intellectual exchanges help accelerate production timelines, reduce costs, and increase chances of bringing an essential vaccine to market. The experts from the M Lab™ Collaboration Centers at MilliporeSigma are no strangers to knowledge sharing and have been involved in supporting a number of successful vaccine development projects. In this GENcast, we talk to a diverse group of public health scientists and discuss their vaccine development projects and how the M Lab Collaboration Centers were able to assist them toward positive outcomes.

    Hosted on Acast. See acast.com/privacy for more information.

    20 min

About GEN Podcasts

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Genetic Engineering & Biotechnology News (GEN) has retained its position as the premier biotech publication since its launch in 1981. GEN publishes a print edition monthly and has additional…