Stephanie Oestreich, a professional Carnegie Hall violinist and biotech leader, shares her journey from Harvard's prestigious labs to leading the Multiple Myeloma Research Foundation Venture Fund. In this insightful interview, Stephanie discusses her disciplined approach to work, influenced by her musical background, and her pivotal role in developing groundbreaking cancer therapies. She explores the importance of precision in medicine, the potential of AI in drug discovery, and creative problem-solving. Additionally, she highlights the value of good habits, diverse teams, and unconventional funding sources in biotech. This conversation illustrates the blend of science, art, and relentless innovation.

In this podcast episode, I share the journey of how my company won a prestigious award previously granted to Nobel Prize winner Jennifer Doudna's startup. The episode covers my transition from management consulting to biotech entrepreneurship, the significance of early morning work hours inspired by David White's poem, my networking efforts and strategic moves to gain acceptance into the prestigious QB3 life science incubator, pivotal moments that led to key mentorships, and the crucial preclinical study results that elevated the Dogma Biotech's status. The story culminates in winning the award and being featured alongside renowned companies in Forbes.

00:00 Introduction: Winning a Prestigious Prize

00:52 The Entrepreneurial Journey Begins

02:26 Networking and Seeking Recommendations

03:50 Entering the Prestigious QB3 Program

04:49 The Impact of QB3 and Winning the Award

05:55 Reflections on the Journey and Early Mornings

In this episode of GenCast, Mark Boulding—Executive Vice President and Chief Legal Officer at PTC Therapeutics—shares the secrets of how he went from law firm partner to the leadership team of a $4B public biotech company. 

Dive deep into strategic negotiations with real-world applications inspired by Chris Voss’ tactics from Never Split the Difference, drawn from Mark's experiences negotiating deals with big pharma. Learn how Mark’s unique approaches to the interpersonal aspects of business negotiations—when to take bold risks and how to manage information flows—have helped shape PTC’s pioneering journey in developing life-saving therapies for individuals living with rare diseases with significant funding from business development deals over more than two decades.

Discover how to use anchoring in non-quantitative contexts, deploy creative dispute resolution techniques like baseball arbitration, and create win-win scenarios using tactical empathy. Get an inside look at how Mark turned challenging situations into groundbreaking successful deals, making biotech negotiations not just a science, but an art form

In this episode of Gencast, Sergio Del Risco delves into the life and philosophy of Ron Cohen, an individual who epitomizes the Renaissance spirit through his deep artistic soul, and his contributions to science and entrepreneurship. Cohen studied at Columbia Medical School, raised USD 1.1 BN in capital, founded and IPOed Acorda Therapeutics, and helped thousands of multiple sclerosis patients to walk. 

Cohen reflects on his unique journey from aspiring actor and singer to accomplished biotechnologist and the founder of Acorda Therapeutics. 

He shares insights from his formative years, influenced by his neurologist father and prodigious violinist mother, and recounts pivotal moments that shaped his path. His narrative is imbued with existential reflections on meaning, purpose, and the courage to act on one's deepest passions. 

Cohen's relentless pursuit of a cure for neurological ailments like multiple sclerosis, despite numerous setbacks, serves as a testament to his belief that true fulfillment comes from embracing the risks and opportunities that life presents. This episode serves as a philosophical exploration of how to live a life that's true to one's potential and passions.

En este episodio discutimos sobre uno de los “Job aplications” más famosos de la historia. En 1482, Leonardo Da Vinci le escribió a Ludovico Sforza, Duque de Milán, ofreciendo sus servicios como ingeniero militar. Sin embargo, Leonardo NUNCA había hecho trabajos en ingeniería militar. 

 ¿Qué enseñanzas nos deja esta historia para el emprendimiento en BIOTECH? Descúbranlo en el nuevo episodio de Gencast

En este episodio relato la historia de cómo caminos inesperados me llevaron a cofundar y convertirme en el CEO de Dogma Biotech, una startup de ingeniería de glicosilaciones en microorganismos para desarrollar soluciones en salud humana. 

El episodio más íntimo de Gencast hasta hoy.

En este episodio, tenemos como invitado Tefo Valdesolo, CEO y co-fundador de DNAZyme 🚀, una empresa que utiliza microorganismos de la Antártida 🧊que son capaces de proteger y restaurar nuestra piel de la radiación solar y UV.

En este episodio aprenderemos como apalancar la evolución y las adaptaciones desarrolladas por organismos en condiciones extremas para desarrollar innovaciones en salud humana. ❄️🧴

 En este episodio exploramos las lecciones del fundador de Nike, Phil Knight, para la construcción de negocios biotech. Discutimos sobre Japón, Psicodélicos y el escalamiento de negocios de biotecnología.

Todo de la mano de nuestra invitada especial: Victoria Costa Paz, fundadora de Eywa, una plataforma biotecnológica para la producción de psiloscibina

¿Qué podemos aprender del Fundador de Nike para el emprendimiento en Biotech?

En el nuevo episodio de Gencast hablamos con las fundadoras de Eywa, una startup que está utilizando bioingeniería para el escalamiento de psicodéliccos. Con su tecnología, Eywa busca revolucionar el tratamiento de condiciones psicológicas como la depresión.

En este episodio discutimos sobre múltiples temas, incluyendo:

- El direct path como corriente filosófiica y su relación con los psicodélicos
- La meditación vs. las experiencias psicodélicas para tratamiento de patologías psicológicas
- La ingeniería de microorganismos para la producción de pscilocibina
- Escalar negocios basados en psicodélicos
- Ciclo de vida de una startup de producción de psicodélicos

En el nuevo episodio de Gencast entrevisto al CTO de ByBug sobre cómo puede utilizarse el metabolismo de los insectos como plataforma para transformar desperdicios industriales en moléculas de alto valor. En este episodio discutimos múltiples temas:
 
 

·       Los insectos como máquinas de producción de moléculas de alto valor agregado

·       Transformación de residuos en proteínas recombinantes

·       Los insectos como reemplazo de biorreactores tradicionales

·       Capacidad productiva de organismos procariotas vs eucariotas

·       Aceleración y escalamiento de empresas basadas en insectos