Genetics

Host: Bruce Bloom, DDS, JD

Guest: David A Greenberg

Dr. David Greenberg, Dir., Division of Statistical Genetics, Professor, Dept. of Biostatistics Mailman School of Public Health and NY State Psychiatric Inst. Columbia-Presbyterian MC,NY is discussing how the use of genetic analysis is improving our understanding epilepsy.

Host: Bruce Bloom, DDS, JD

Guest: David A Greenberg

Dr. David Greenberg, Director, Division of Statistical Genetics, Professor, Dept. of Biostatistics Mailman School of public Health and NY State Psychiatric Institute Columbia- Presbyterian MC, NY is discussing how computer simulations can help find genes that influence diseases.

Host: Bruce Bloom, DDS, JD

Guest: David A Greenberg

Dr. David Greenberg, Dir. , Division of Statistical Genetics,Professor, Dept. of Mailman School of Public Health and New York State Psychiatric Institute Columbia- Presbyterian Medical Center in NY, will be discussing the power and problems of finding genes that influence disease.

Host: Bruce Bloom, DDS, JD

Guest: Jeffrey Settleman, PhD

These days treatment decisions often rely on genetics and biomarkers. Are we entering the age of personalized medicine? Dr. Bruce Bloom hosts.

Host: Bruce Bloom, DDS, JD

Guest: Jeffrey Settleman, PhD

We’ve been fighting cancer for almost 50 years without real success. Could molecular targeted drugs finally be the answer?

Host: Larry Kaskel, MD

Guest: Elizabeth Tieman, MD

Work-life balance: how many of us can say we have it, let alone come close to having it? Board-certified radiologist Dr. Betsy Tieman is one healthcare professional who can say she achieved work-life balance by leaving private practice where she was working 14 hours a day to take advantage of locum tenens work, which also enabled her to train and compete in triathlons.

Host: Michael Benson, MD

Guest: J. Lee Nelson, MD

Microchimerism may have a role to play in evolving theories in transplantation biology, HIV, Alzheimer's disease and even breast cancer. Dr. Nelson discusses some cutting-edge hypotheses and strange observations in each of these fields.

Host: Michael Benson, MD

Guest: J. Lee Nelson, MD

While the transfer and persistence of fetal cells into the maternal circulation is counter-intuitive, an even stranger occurrence is the reverse. Dr. Nelson discusses the evidence that maternal cells are transferring into the fetus. In the case of neonatal lupus it appears that maternal stem cells differentiate into cardiac tissue and might incite a deleterious fetal immune response. In the case of juvenile diabetes, maternal stem cells may differentiate into islet cells that can produce insulin. It appears that this might mitigate the course of the disease.

Host: Michael Benson, MD

Guest: J. Lee Nelson, MD

Fetal cells persisting in maternal tissues for 50 years and then causing a graft versus host reaction? Medicine does not get more bizarre, but this seems to be the case for systemic sclerosis. Dr. Nelson examines the growing evidence to support this new look at some of the "auto-immune" diseases.

Host: Michael Benson, MD

Guest: J. Lee Nelson, MD

Rheumatoid arthritis often improves during pregnancy. Why? Truth is stranger than fiction here as it seems that that immunologically competent fetal cells transferring into the maternal circulation help mitigate the mother's immune response to "self."