In this episode, we explore key pharmacologic agents affecting the gastrointestinal system and immune function, connecting drug mechanisms to nursing practice. We’ll review major GI medication classes, including antacids (like Mylanta), GI protectants (Sucralfate), and prostaglandins (Misoprostol)—covering their indications, contraindications, and common adverse effects. The discussion then shifts to antivirals (such as Lamivudine and Adefovir) and immune stimulants (including Interferons and Ribavirin), with a focus on mechanisms of action, major toxicities, and Black Box Warnings. We’ll also touch on complementary medicine, highlighting Milk Thistle as a natural option for liver health. This episode provides a practical guide for nursing students to understand drug actions, safety precautions, and patient teaching points essential for pharmacology success.