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Eli Lilly's once-daily oral GLP-1 orforglipron showed no excess cardiovascular risk against insulin glargine in the 2,749-patient ACHIEVE-4 trial, published in The Lancet. That clears a key regulatory hurdle, while an NEJM perspective warns that obesity drug trials aren't built to detect emerging harms.
In this episodeDaily TopFive for GLP-1 Daily: Ozempic & Wegovy News. Links above go to the original articles. Follow and rate GLP-1 Daily: Ozempic & Wegovy News on Apple Podcasts. Feedback? Email [email protected].
An American Academy of Ophthalmology meeting study links GLP-1 use to faster second-eye NAION, as federal eye-injury cases climb to 247; plus Medicare Bridge paperwork gaps for cash-pay patients, pharmacists seeing more cash GLP-1 fills, the WHO's first childhood obesity guidelines, and Korea's first homegrown GLP-1 obesity drug.
In this episodeGLP-1 Drugs Linked to Faster Vision Loss in the Second Eye, New Study Finds | Newswise
Medicare’s Missing On-Ramp For Access To GLP-1s For Weight Management | Health Affairs
Patients increasingly bypass insurance to pay cash for GLP-1 prescriptions, pharmacists say
Should kids living with obesity be on GLP-1s? New global guidance says yes — in some cases
MFDS approves Hanmi's EPPE, Korea's first homegrown GLP-1 obesity drug · Local Chorus
Daily TopFive for GLP-1 Daily: Ozempic & Wegovy News. Links above go to the original articles. Follow and rate GLP-1 Daily: Ozempic & Wegovy News on Apple Podcasts. Feedback? Email [email protected].
Medicare's $50-a-month GLP-1 Bridge pilot is denying some obese seniors who have certain diagnoses, such as severe sleep apnea. Separately, Amylyx will present Phase 3 avexitide data for post-bariatric hypoglycemia at ObesityWeek in November.
In this episode# Amylyx to Present Phase 3 LUCIDITY Data at ObesityWeek | AMLX Stock News
# The Medicare GLP-1 Discount Has One Big Catch: Some Sick Patients Don’t Qualify | Sleep Review
Daily TopFive for GLP-1 Daily. Links above go to the original articles. Follow and rate GLP-1 Daily on Apple Podcasts. Feedback? Email [email protected].
Federal employee health plans will require documented intensive behavioral therapy before and during anti-obesity drug treatment in 2027, while the new ADA-EASD consensus backs GLP-1 or SGLT2 drugs early in type 2 diabetes. Plus a phase 3 oral GLP-1 pill, a new SELECT heart analysis, and what's known about GLP-1s in children.
In this episode# 2027 FEHB Changes: Weight Loss Drug Rules, A New FSA Card, And Plans Leaving | FedSmith.com
The 2026 Diabetes Consensus Backs GLP-1 or SGLT2 Drugs Early, Possibly From Diagnosis, Without Waiting on Metformin | Peptide News Digest
# Oral small-molecule GLP-1RA safiglipron versus dapagliflozin in type 2 diabetes: a randomized, double-blind, active-comparator-controlled phase 3 trial | Nature Medicine
Semaglutide heart benefits not fully explained by weight loss - The Pharmacist
Weight loss GLP-1s are everywhere and kids are taking them too. 7 things parents should know – PolitiFact
Daily TopFive for GLP-1 Daily. Links above go to the original articles. Follow and rate GLP-1 Daily on Apple Podcasts. Feedback? Email [email protected].
Rhode Island Medicaid stopped covering GLP-1s prescribed only for weight loss on October 1, and new Massachusetts data shows weight-loss use fell 52% after insurers pulled back. Plus Cigna employees pressing their own employer, a physician's case against the compounding market, and semaglutide's benefits across frailty levels.
In this episode# Rhode Island Medicaid Ends Coverage of Wegovy, Zepbound, and Other GLP-1 Drugs Prescribed Only for Weight Loss
Insurers Cut Coverage — GLP‑1 Weight‑Loss Use in Massachusetts Falls 52%, Impacting 112,000 Patients - CRBC News
OAC Calls on Cigna to Listen to Employees and Restore GLP-1 Coverage
# I'm an obesity expert and can't wait for the compounding craze to stop | Fortune
Semaglutide Demonstrates Benefits Across Frailty Levels | Obesity | JAMA | JAMA Network
Daily TopFive for GLP-1 Daily. Links above go to the original articles. Follow and rate GLP-1 Daily on Apple Podcasts. Feedback? Email [email protected].
A JAMA Health Forum study finds GLP-1 nonadherence tops 80% once monthly out-of-pocket costs pass $75, while New Mexico's Medicaid Ozempic spending hit $38.7 million in 2025. Plus survodutide's Phase 3 in NEJM, the amylin tolerability tradeoff, and Novo's injection-to-pill switch data.
In this episodeHigher GLP-1 costs lead to lower adherence | EurekAlert!
Ozempic driving massive increase in New Mexico Medicaid prescription drug spending | Local News | santafenewmexican.com
Zealand Pharma announces Boehringer Ingelheim’s survodutide achieves up to 13.1% weight loss in new Phase III trial, alongside significant improvements in glycemic control in people with obesity and type 2 diabetes - BioSpace
# Novel amylin drug confers 10% weight loss, well tolerated
# People switching from weight-loss injections to Novo's Wegovy® pill lost 4.1% body weight on average after three months, according to real-world data presented at EASD2026
Daily TopFive for GLP-1 Daily. Links above go to the original articles. Follow and rate GLP-1 Daily on Apple Podcasts. Feedback? Email [email protected].
Zepbound is back on CVS Caremark's standard commercial formulary starting October 1, but employers still decide, while Massachusetts critics press the state to undo its GLP-1 weight-loss coverage cuts. Plus a JAMA Health Forum Medicaid study on prior authorization, Lilly-sponsored ACHIEVE-4 heart-safety data for Foundayo in The Lancet, and California's new CalRx GLP-1 law.
In this episodeCVS Caremark Adds Zepbound Back October 1, 2026: What to Ask HR Before Open Enrollment
# Critics say GLP-1 coverage shift raises equity issues
# Medicaid Coverage of Obesity GLP-1s May Shift From Diabetes Version
Lilly's oral GLP-1, Foundayo (orforglipron), demonstrated cardiovascular safety alongside sustained A1C reduction and weight loss in its largest and longest type 2 diabetes study
Newsom signs law allowing California-made GLP-1 drugs
Daily TopFive for GLP-1 Daily. Links above go to the original articles. Follow and rate GLP-1 Daily on Apple Podcasts. Feedback? Email [email protected].
Counterfeit Ozempic allegedly sourced from China is at the center of a federal indictment of two Indian nationals in Tampa. At EASD in Milan, Lilly-funded Phase 3 retatrutide results appear in The Lancet, and a Novo-funded registry study finds no semaglutide–pancreatic cancer link.
In this episodeTwo Indicted in Florida for International Counterfeit Ozempic Smuggling Scheme | The Front Page
Lilly's triple agonist, retatrutide, delivered substantial weight loss and A1C reduction, underscoring its potential promise for people with obesity and type 2 diabetes
Novo, Lilly unleash dueling GLP-1 datasets at EASD in Milan
Regulator-mandated study finds no link between semaglutide use and pancreatic cancer using nationwide registry data from Denmark, Sweden and Norway | EurekAlert!
Daily TopFive for GLP-1 Daily. Links above go to the original articles. Follow and rate GLP-1 Daily on Apple Podcasts. Feedback? Email [email protected].
Zealand Pharma and Roche have launched a roughly 7,000-person Phase 3 program for once-weekly petrelintide in obesity. Meanwhile, a baseline 100 percent Section 232 tariff on imported patented medicines and ingredients takes effect and EASD convenes in Milan.
In this episodeGlobal Registrational Phase 3 ZUPREME Program Evaluating Petrelintide in Overweight or Obesity Initiated – Zealand Pharma - Medical Update Online
Navigating Pharma’s Forced Supply Chain Revolution - Chemistry Today
EASD 2026 to Feature New Diabetes Approaches in T1DM, T2DM, obesity - Dagensdiabetes
Amye Joseph says America’s political polarization has made it an “interesting time” in her Tennessee household. She and her husband, Charlie, have been married 35 years. She’s a Republican. He’s a Democrat. But their shared disenchantment with profit-driven healthcare has provided a unifying target: pharmacy benefit managers, known as PBMs. The Josephs’ frustration is focused on CVS Health. The…
Oral solid dose at a turning point: Scaling for the next generation of therapies - Pharmaceutical Technology
Daily TopFive for GLP-1 Daily. Links above go to the original articles. Follow and rate GLP-1 Daily on Apple Podcasts. Feedback? Email [email protected].
Mylan is asking a Delaware court to clear its proposed generic Wegovy from a new Novo Nordisk patent. Twenty state attorneys general are warning the White House about Chinese GLP-1 ingredient suppliers, and doctors are flagging a rare vision-loss risk still under study.
In this episodeMylan asks US court to clear Wegovy generic from Novo patent claims | Reuters
Tennessee AG Skrmetti Joins 20-State Warning over Chinese Weight-Loss Drug Suppliers Linked to Fentanyl Precursors - Tennessee Star
Doctor warns of 'eye stroke' risk linked to GLP-1 weight loss drugs - Health - News - Daily Express US
Daily TopFive for GLP-1 Daily. Links above go to the original articles. Follow and rate GLP-1 Daily wherever you listen. Feedback? Email [email protected].
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