Health Files With Dr. Miles

Tanner, Jade, and Dr. Miles bring you news of a brand-new cancer treatment. It looks so promising that the stock price of the company that makes it has gone up 10x over the past year.

mRNA Vaccine to Treat Cancer:

• Adding mRNA vaccine to a proven cancer treatment reduced bad outcomes by 45% in deadly melanoma.
• Learn how the same COVID vaccine technology is harnassed to fight cancer.
• Side effects are generally less than traditional chemotherapy.
• Phase 3 trials are complete with likely FDA approval sought next.

We hope you join us as we dive deep into medicine so you don't have to. You stay safe (and informed) swimming in the shallows. We present the best studies and research in easy to understand and entertaining ways . We are telling our personal findings and stories and not giving medical advice . We are not a substitute for your doctor .

We gladly accept show topics and ideas from our listeners: [email protected]

Some of the resources used in this episode:

mRNA Vaccines in Melanoma Immunotherapy—A Narrative Review https://www.mdpi.com/2073-4409/15/3/298

Merck and Moderna Announce Phase 3 INTerpath-001 Trial of Intismeran Autogene Plus KEYTRUDA® Met Endpoints of Recurrence-Free Survival (RFS) and Distant Metastasis-Free Survival (DMFS) in Patients With Completely Resected Stage IIB-IV Melanoma https://news.modernatx.com/merck-and-moderna-announce-phase-3-interpath-001-trial-of-intismeran-plus-keytruda-met-endpoints-of-rfs-and-dmfs-in-melanoma

Tanner, Alyssa, and Dr. Miles bring the serious topic of Major Depressive Disorder to the forefront with an effective, affordable, easy, and essentially side effect-free treatment.

Bright Light Therapy for Depression:

• Adding a simple 10,000-lux white light device to standard treatment can double the odds of remission.
• Learn how easy it is to use (and how it can be completely free.)
• Light has a surprising impact on dementia risk.

Hyperhidrosis (Excessive Sweating)

• New research shows the root cause lies deep within the nervous system's sodium channels rather than the skin.
• A medicine that already exists might treat it.

We hope you join us as we dive deep into medicine so you don't have to. You stay safe (and informed) swimming in the shallows. We present the best studies and research in easy to understand and entertaining ways . We are telling our personal findings and stories and not giving medical advice . We are not a substitute for your doctor .

We gladly accept show topics and ideas from our listeners: [email protected]

Some of the resources used in this episode.

Bright Light Therapy for Nonseasonal Depressive Disorders: A Systematic Review and Meta-Analysis https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2824482

Associations between wearable-device-measured daytime and nighttime light exposures and dementia risk: A prospective cohort study https://onlinelibrary.wiley.com/doi/full/10.1002/gps3.70039

Excessive Sweating May Start in Nervous System https://www.hopkinsmedicine.org/news/newsroom/news-releases/2026/07/excessive-sweating-may-start-in-nervous-system-new-study-finds

Tanner, Jade, and Dr. Miles discuss the real impact for you on the latest guidelines of cholesterol.

The new guidelines on cholesterol and heart disease are over 120 pages (and boring.) We break them down and delivery the important info in a simple, easy-listening format (with entertainment and questions from Tanner.)

Learn:

• The new tests that may better predict your risk of heart disease.
• How 1 in 5 people have a secret heart disease amplifier.
• How a popular "natural" cholesterol supplement actually contains a Statin.
• Whether or not your blood levels of cholesterol affect your brain health.

Have a question or a topic you want us to cover? We want to hear from you! Drop us a line at [email protected].

Just one of the resources used with this episode:

https://www.ahajournals.org/doi/10.1161/CIR.0000000000001423

So you "don't have time for exercise"?

In this episode Tanner, Alyssa, and Dr. Miles discuss the latest research on exercise amounts for wellness.

Learn:

• About an 8-year study of over 70,000 people looking for the most powerful type of exercise.
• How the health benefits of walking at a mall for over an hour can actually be accomplished in 1 minute.
• How just 15 minutes per week of exercise makes a big difference, if you choose the right type.

Have a question or a topic you want us to cover? We want to hear from you! Drop us a line at [email protected].

Just one of the resources used with this episode:

Wearable device-based health equivalence of different physical activity intensities against mortality, cardiometabolic disease, and cancer. https://www.nature.com/articles/s41467-025-63475-2

Is your pain medicine actually prolonging your recovery?

In this episode Tanner, Jade, and Dr. Miles get to the bottom of:

• Is skipping late-night snacks the secret to lowering your blood pressure and heart attack risk?
• How many hours do you really need to fast to make a difference?
• How the standard treatment of injuries may make your pain worse?

Have a question or a topic you want us to cover? We want to hear from you! Drop us a line at [email protected].

Just a few of the resources used with this episode:

Suppressing Postoperative Inflammation May Prolong Pain. https://msutoday.msu.edu/news/2026/01/suppressing-post-op-inflammation-may-prolong-pain?collectionName=Medical%20Breakthroughs

Sleep-Aligned Overnight Fasting Linked to Cardiometabolic Benefits. https://www.ahajournals.org/doi/abs/10.1161/ATVBAHA.125.323355

Can you starve your cancer away? (The type of cancer may matter)

Welcome to another info-packed episode with Tanner, Alyssa, and Dr. Miles.

• Does fasting really increase the chances of destroying cancer by 3.5 times (250%)?
• Will a special type of fasting be added to the cancer guidelines, or is it too risky?
• Is "Increase your water intake" really the best option for kidney stone prevention?
• Why is a seldom-used (and very effective) cheap medicine rarely used to prevent kidney stones? Does lemon juice work?

Find out the answers to all these questions now.

At HFWDM, we do the deeps dives into the latest and greatest medical research so you don't have to. Our goal is to bring you cutting edge and peer-reviewed science in a way that is easy to understand, practical, and entertaining.

Have a question or a topic you want us to cover? We want to hear from you! Drop us a line at [email protected].

Just a few of the resources used with this episode:

Can Fasting Around Chemo Improve Ovarian Cancer Outcomes? https://www.medscape.com/viewarticle/can-fasting-around-chemo-improve-ovarian-cancer-outcomes-2026a1000h20?ecd=a2a

Prevention of urinary stones with hydration: a randomised clinical trial of an adherence intervention. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)02637-6/abstract

Listen to the big news on Alzheimer's dementia as Tanner, Alyssa, and Dr. Miles go into the nitty gritty of a promising study and drug.

• Did Tanner, Alyssa, and Dr. Miles find a cure for Alzheimer's dementia that actually will pan out for humans?
• Are you down with NAD (and ATP)? Yeah, you know me.
• How does the HFWDM team feel about the Keto Diet?
• What's easier to grow than sweet potatoes?

Find out the answers to all these questions now.

At HFWDM, we do the heavy lifting in the deep waters of medical research so you don't have to. Our goal is to bring you cutting edge and peer-reviewed science in a way that is easy to understand, practical, and entertaining.

Have a question or a topic you want us to cover? We want to hear from you! Drop us a line at [email protected].

Just one of the resources used with this episode:

Pharmacologic reversal of advanced Alzheimer's disease in mice and identification of potential therapeutic nodes in human brain https://www.sciencedirect.com/science/article/pii/S2666379125006081

Can sitting in a 200°F oven really cut your cardiovascular and dementia risk in half?

In this episode, we:

• Break down the landmark Finnish cohort study that turned sauna into a serious longevity intervention
• Dive into the science of how extreme heat impacts your body chemistry and anatomy
• Explore more recent follow-up research and results
• Look at the real-world data tracking from "Don't Die" tech entrepreneur Bryan Johnson's rigorous Blueprint protocol
• Learn why you might need an Ice Diaper

Welcome to another info-packed episode with Tanner, Jade, and Dr. Miles.

At HFWDM, we do the heavy lifting in the deep waters of medical research so you don't have to. Our goal is to bring you cutting-edge and peer-reviewed science in a way that is easy to understand, practical, and entertaining.

Have a question or a topic you want us to cover? We want to hear from you! Drop us a line at [email protected].

One (the big one) of the many resources used with this episode:

Association Between Sauna Bathing and Fatal Cardiovascular and All-Cause Mortality Events https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2130724

Welcome to another info-packed episode with Tanner, Alyssa, and Dr. Miles.

• Is Tanner secretly a bear? And does it make him more or less at risk for heart disease?
• Your sleep chronotype may increase your chances of a heart attack and stroke. Which type are you?
• What is better: natural fiber or those designed in a lab? Metacucil is a natural supplement. but not FiberCon is synthetic.
• Health monitoring wearables are everywhere. We discuss the experience of Dr. Miles with glucose monitors, but what is the new wearable that diagnoses skin cancer?

Find out the answers to all these questions now.

At HFWDM, we do the heavy lifting in the deep waters of medical research so you don't have to. Our goal is to bring you cutting edge and peer-reviewed science in a way that is easy to understand, practical, and entertaining.

Have a question or a topic you want us to cover? We want to hear from you! Drop us a line at [email protected].

Just a few of the resources used with this episode:

Fake Fiber or Whole Fiber: Does it Matter? https://www.medscape.com/viewarticle/fake-fiber-or-whole-fiber-does-it-matter-2026a10004a4?ecd=wnl_tp10_daily_260214_MSCPEDIT_etid8103246&uac=359050DN&impID=8103246

Night Owls May Face Significantly Higher Cardiovascular Risk https://www.ahajournals.org/doi/10.1161/JAHA.125.044189

Researchers develop wearable patch for early skin cancer detection https://newsroom.wakehealth.edu/news-releases/2025/10/researchers-develop-wearable-patch-for-early-skin-cancer-detection

Welcome to another info-packed episode with Tanner, Jade, and Dr. Miles.

• How did Tanner earn his new nickname?!!
• Why is colon cancer being seen so often and more aggressive in people younger than 50?
• People use caffeine to help their brains function better. But what about the long term? What is the association of coffee and tea on dementia?
• Ivermectin: will a new study show that it helps treat cancer?

Find out the answers to all these questions now.

At HFWDM, we do the heavy lifting in the deep waters of medical research so you don't have to. Our goal is to bring you cutting edge and peer-reviewed science in a way that is easy to understand, practical, and entertaining.

Have a question or a topic you want us to cover? We want to hear from you! Drop us a line at [email protected].

Just a few of the resources used with this episode:

Leading Cancer Deaths in People Younger Than 50 Years https://jamanetwork.com/journals/jama/fullarticle/2844189

US Cancer Institute Studying Ivermectin's 'Ability to Kill Cancer Cells' https://www.medscape.com/s/viewarticle/us-cancer-institute-studying-ivermectins-ability-kill-cancer-2026a10004c2?ecd=wnl_tp10_daily_260212_MSCPEDIT_etid8098670&uac=359050DN&impID=8098670

Coffee and Tea Intake, Dementia Risk, and Cognitive Function https://jamanetwork.com/journals/jama/article-abstract/2844764