In this episode:

• How gene therapy works

• The conditions for which gene therapy is currently approved

• The future direction of gene therapy and in particular its potential for treating conditions such as Angelman Syndrome

Expert: Prof David Segal, Biochemistry and Molecular Medicine, Pharmacology

This podcast is intended to be medical advice that is designed for health professionals only. We do not recommend you use this podcast as a substitute for a consult with a qualified health professional.

Foundation for Angelman Syndrome Therapeutics (FAST) is committed to assisting individuals living with Angelman syndrome to realise their full potential and quality of life. Their ultimate goal is to cure Angelman syndrome with a focus on global research, clinician network initiatives, addressing underdiagnosis and contributing to ongoing education of the condition. cureangelman.org.au/

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In this episode:

• SCAD is the leading cause of heart attacks in women under 50, often caused by bleeding in the artery wall that leads to tearing

• SCAD is linked to genetic factors affecting collagen and tissue strength, with emotional stress being a common trigger
• Diagnosis can be challenging, as young women with chest pain aren't typically suspected of having heart attacks; troponin testing is crucial for detection
• Unlike atherosclerosis, SCAD is treated conservatively with beta blockers (preferably long-term) and limited use of antiplatelet therapy
• The risk of recurrence is 20-30%, and prevention includes beta blockers, treating high blood pressure, and screening for fibromuscular dysplasia

Expert: Dr Jason Kovacic, Clinical Cardiologist

This podcast is intended to be medical advice that is designed for health professionals only. We do not recommend you use this podcast as a substitute for a consult with a qualified health professional.

SCAD Research Inc is a charity dedicated to changing the outcome for SCAD heart attack sufferers. Founded and run by heart attack survivors, they are on a mission to improve the diagnosis, treatment and survival rates for every mum, sister, dad, brother or friend who suffers a heart attack – to save their life and minimise the chances of recurrence. https://scadresearch.com.au/

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In this episode:

• There are four formulations of thyroxine available – understand the differences and the practical implications
• How to initiate thyroxine in the elderly, the newly pregnant woman and an otherwise healthy young adult
• How to monitor progress
• Excluding subclinical hypothyroidism in pregnancy is critical

Expert: Prof Creswell Eastman AO, Endocrinologist

This podcast is intended to be medical advice that is designed for health professionals only. We do not recommend you use this podcast as a substitute for a consult with a qualified health professional.

EMERITUS PROFESSOR CRESWELL EASTMAN AO (1940-2025)

Emeritus Professor Creswell Eastman AO, Endocrinologist, was respected worldwide for his dedication to global prevention of iodine deficiency and thyroid disorders. Professor Eastman's podcasts focus on thyroid health, pregnancy and foetal outcomes and are relevant today as they have always been.

Visit Australian Thyroid Foundation for patient resources, individual support and information about the consequences of thyroid disease, iodine deficiency and the benefits of achieving good thyroid health. www.thyroidfoundation.org.au/ 

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In this episode:

• Be aware of voice disorders and ask patients about them
• Don’t start treatment, or provide antibiotics or steroids without diagnosis
• Understand the bigger picture, the patient and impact in the initial consultation
• Be aware of underlying potential, if it has been an issue for more than 4 weeks, send patients to specialists to make a diagnosis and start the right treatment

Experts: A/Prof Daniel Novakovic, Otolaryngologist

Judith Rough, Speech Pathologist

Louise Bale, Senior Health Promotion Officer

This podcast is intended to be medical advice that is designed for health professionals only. We do not recommend you use this podcast as a substitute for a consult with a qualified health professional.

The Australian Dysphonia Network Inc is a not-for-profit organisation run by, and for, people affected by voice disorders. They provide support and help to others affected by dysphonia, while educating, lobbying and raising awareness of voice disorders within the community and the medical profession. https://australiandysphonianetwork.org/

 

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In this episode:

• Even mild primary hyperparathyroidism significantly increases CV mortality
• Minimally invasive surgery has become the recommended treatment - where the surgery is done and by whom is critically important for the 10% of cases that are difficult
• Do a serum calcium and PTH for patients with unspecific neurocognitive, neuromuscular and renolithiasis or low BMD
• Normo calcaemic hyperparathyroidism may be caused by primary HPT or secondary and a therapeutic / diagnostic trial with 2,000 IU of vitamin D3 for 3 months will disclose the cause
• Image with ultrasound and parathyroid 4DCT angiogram

Expert: Prof Leigh Delbridge, Parathyroid and Thyroid Surgeon

This podcast is intended to be medical advice that is designed for health professionals only. We do not recommend you use this podcast as a substitute for a consult with a qualified health professional.

Visit Australian Thyroid Foundation for patient resources, individual support and information about the consequences of thyroid disease, iodine deficiency and the benefits of achieving good thyroid health. www.thyroidfoundation.org.au/ 

See omnystudio.com/listener for privacy information.

In this episode:

• Why sleep patterns may be altered during pregnancy

• The effects of sleep disturbance on both maternal and fetal outcomes

• Recommended sleep positions at various stages of pregnancy

• Tips for optimising sleep during pregnancy

Expert: Dr Danielle Wilson, Postdoctoral Research Fellow

This podcast is intended to be medical advice that is designed for health professionals only. We do not recommend you use this podcast as a substitute for a consult with a qualified health professional.

The Australasian Sleep Association (ASA) is the peak scientific body in Australia and New Zealand representing clinicians, scientists and researchers working in sleep health and sleep medicine. Visit the Australasian Sleep Association for more information and resources. https://www.sleep.org.au/

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In this episode:

• Recognise that insomnia and sleep apnoea do frequently co-occur
• 40-50% of patients with either condition have both
• If both insomnia and sleep apnoea occur in any patients, it is recommended to provide access for assessment diagnostic and treatment pathways

Expert: Dr Alexander Sweetman, Senior Program Manager & Research Fellow

This podcast is intended to be medical advice that is designed for health professionals only. We do not recommend you use this podcast as a substitute for a consult with a qualified health professional.

The Australasian Sleep Association (ASA) is the peak scientific body in Australia and New Zealand representing clinicians, scientists and researchers working in sleep health and sleep medicine. Visit the Australasian Sleep Association for more information and resources. https://www.sleep.org.au/

See omnystudio.com/listener for privacy information.

In this episode:

• How can GP’s better support & manage their thyroid patients?
• How to achieve the optimal dose
• Overcoming barriers to patient compliance
• How often should we do blood tests/monitoring?

Expert: Prof Creswell Eastman AO, Endocrinologist

This podcast is intended to be medical advice that is designed for health professionals only. We do not recommend you use this podcast as a substitute for a consult with a qualified health professional.

EMERITUS PROFESSOR CRESWELL EASTMAN AO (1940-2025)

Emeritus Professor Creswell Eastman AO, Endocrinologist, was respected worldwide for his dedication to global prevention of iodine deficiency and thyroid disorders. Professor Eastman's podcasts focus on thyroid health, pregnancy and foetal outcomes and are relevant today as they have always been.

Visit Australian Thyroid Foundation for patient resources, individual support and information about the consequences of thyroid disease, iodine deficiency and the benefits of achieving good thyroid health. www.thyroidfoundation.org.au/ 

See omnystudio.com/listener for privacy information.

In this episode:

• The importance of accurately diagnosing mild cognitive impairment early
• Lifestyle & CVD risk factor modification are important with the Mediterranean diet, and medical food Souvenaid showing benefits if taken daily for three years
• The importance of reducing the burden of anticholinergic agents being taken
• Soon there will be monoclonal antibody therapy aimed at reducing amyloid plaque, which has delayed progression of cognitive impairment, however accurate diagnosis will be required to access these agents
• We believe the patient can die with the disease, and not because of the disease

Expert: Prof Michael Woodward AM, Geriatrician

This podcast is intended to be medical advice that is designed for health professionals only. We do not recommend you use this podcast as a substitute for a consult with a qualified health professional.

See omnystudio.com/listener for privacy information.

In this episode:

• Advice on oestrogen dosing during the pill-free interval for women on OCPs

• Non-hormonal option for hot flushes, effectiveness, dosage, and where it fits in treatment

• Testosterone in women under 50: current indications and what patients notice first

• Case-based insights on POI, osteoporosis risk, and MHT decisions in complex scenarios

• Tips for safely managing progesterone regimens – continuous daily use vs the traditional 25-day cycle

Expert: Prof Rodney Baber AM, Gynaecologist

This podcast is intended to be medical advice that is designed for health professionals only. We do not recommend you use this podcast as a substitute for a consult with a qualified health professional.

See omnystudio.com/listener for privacy information.