Hospitals can't reliably get their own protocols to the bedside. Dr. Ido Zamberg of C8 Health on the 17-year evidence gap and fixing clinical knowledge chaos.

Episode Resources:

• Official Website for C8 Health

Every clinician knows the feeling: you need a protocol, and you have no idea where it lives. Maybe it's a PDF on a shared drive. Maybe it's an intranet page nobody's updated since 2019. Maybe it's a printout taped to a bulletin board with a phone number for a coordinator who left last year. Medicine is the most knowledge-intensive profession there is, and yet hospitals — good at care delivery, billing, regulatory compliance, and training residents — are not built to be knowledge organizations. The EMR doesn't solve it either. It's excellent at patient-level data and transactions, and largely silent on institutional know-how.

This week, we dig into C8 Health, an AI-powered best practices implementation platform tackling exactly that gap, and talk with co-founder and Chief Medical Officer Dr. Ido Zamberg. Zamberg's path is unusual: a senior developer at HP, Mercury Interactive, and Autodesk — where his specialty was optimizing access to information across large enterprises — who became an anesthesiologist and medical educator. He traces the idea back to a specific moment on geriatric rounds, watching colleagues each build their own ad hoc checklists for the same admission, all slightly differently, all because the hospital's actual protocols were impossible to find. The tool he built for his own department spread across five hospitals.

The conversation gets into where generative AI genuinely fits here — a retrieval-grounded assistant answering from vetted institutional content, with citations down to the paragraph, rather than a general-purpose chatbot improvising clinical advice. Zamberg also makes a pointed argument about quality improvement: that hospitals spend heavily on extracting quality data, then lock it in dashboards that individual providers never see, and pair it with one-time interventions that decay almost immediately. With new evidence taking an average of 17 years to reach practice, ERAS compliance hovering near 50% nationally, and more than 70% of quality interventions failing to sustain, the case that this is fundamentally a distribution problem is a hard one to argue with.

apree health CMO Dr. Marla McLaughlin on merging Castlight navigation with Vera advanced primary care – and why prevention pays off by year three.

Episode Resources:

• Official Website for apree health
• apree health’s Expansion of Clinical Advocacy Services

What if fixing employer healthcare isn't about adding another point solution, but about connecting the ones you already have?

This week, Trevor and Tim break down apree health – the company born from Castlight Health's digital navigation and Vera Whole Health's advanced primary care – and ask whether it's a benefits platform or a true closed-loop care model. Then they're joined by Paul for a conversation with apree health Chief Medical Officer Dr. Marla McLaughlin.

Dr. McLaughlin shares her path from fee-for-service community medicine to leading care at the intersection of national virtual care and local, relationship-based primary care. Along the way: why the "apparently healthy" employee is the population everyone overlooks, why prevention doesn't show savings until year three or four, how AI scribes are giving physicians back the art of medicine, and where the human still has to step in when the algorithm reaches its limit. A candid look at benefits complexity, value-based care, and what the next generation of primary care could actually deliver.

Discover the future of longevity medicine with Cenegenics. Learn how advanced diagnostics, hormone optimization, and coaching can maximize your healthspan.

Episode Resources:

• Cenegenics
• JAMA Study on VO2 Max and Long-Term Survival
• Medicine 3.0 and Healthspan Optimization by Peter Attia
• Understanding Lp(a) and Advanced Cardiovascular Risk Markers
• Medicare Guidelines for Preventive and Wellness Services

Long before the current wave of biohacking and longevity startups, Cenegenics was quietly pioneering the performance health movement. In this episode of HealthTech Remedy, we sit down with Rudy Inaba, VP of Performance Health at Cenegenics, to unpack the science of health optimization and proactive aging. You’ll learn how to transition from reactive, episodic care to a proactive medical framework that maximizes physical, cognitive, and metabolic healthspan. 

We explore how Cenegenics uses a concierge medicine model to deliver high-touch, longitudinal care driven by comprehensive biomarker tracking, epigenetics, and advanced diagnostics. Rudy breaks down the nuance of modern hormone optimization, detailing why managing cortisol and lifestyle habits is often more critical than jumping straight to testosterone therapy. He also shares why improving your VO2 max is the ultimate biological retirement plan and how continuous behavioral coaching bridges the gap between complex data and actual health outcomes. Discover which specific metrics are essential for measuring the epigenetic "software" running on your genetic "hardware" so you can start building a more resilient body today.

If you are ready to start treating your healthspan as your most valuable asset, hit subscribe to HealthTech Remedy and leave us a review!

CEO Alok Tayi shares how Vibe Bio uses AI in drug development to automate due diligence, solve the biotech funding cliff, and accelerate rare disease cures.

Episode Resources:

• Official Website for Vibe Bio
• Nature Article on the "Valley of Death" in Drug Development
• "Chasing My Cure" by David Fajgenbaum

While most AI biotech startups focus on discovering new molecules, the industry's real bottleneck is deciding which existing therapies actually secure the capital to reach patients. In this episode of HealthTech Remedy, we sit down with Dr. Alok Tayi, founder and CEO of Vibe Bio, to explore how artificial intelligence is completely transforming the multi-billion-dollar pharmaceutical due diligence process. Tune in to discover how data-driven investing is rescuing promising treatments from the "funding cliff" and rewriting the economics of drug development. 

Driven by a personal mission after his daughter’s rare disease diagnosis, Dr. Tayi explains how traditional biopharma funding models systematically overlook high-need communities in favor of massive, crowded markets. We unpack how Vibe Bio’s proprietary AI platform, VibeOne, processes preclinical data and trial designs to automate deep due diligence, stripping away human bias while aiming to double clinical success rates from 10% to 20%. The conversation also tackles the evolving landscape of tech bio, the delicate balance between machine computation and human strategic judgment, and why geopolitical competition is forcing a much-needed evolution in regulatory agility. Will AI finally democratize biotech funding, or is the most critical element of drug development still fundamentally human?

If you want to stay ahead of the curve on the latest innovations shaping the future of care, make sure to subscribe and leave a review for Health Tech Remedy!

Can AI reverse metabolic disease? Discover how Twin Health uses digital twins to safely reduce GLP-1 reliance and personalize care in this podcast episode.

Episode Resources:

• Twin Health
• NEJM Catalyst Study on AI-Enabled Diabetes Remission
• Genome Medicine Article on Digital Twins in Personalized Medicine
• ADA Consensus Report on Defining Type 2 Diabetes Remission
• JAMA Study on Weight Regain After GLP-1 Discontinuation
• Cleveland Clinic Newsroom Summary of Twin Health Research

What if you could predict exactly how your body would react to a specific meal before taking a single bite? In this episode of HealthTech Remedy, we sit down with Dr. Lisa Shah to explore how Twin Health is using digital twin technology to actually reverse - rather than just manage - chronic metabolic diseases. Tune in to discover how continuous data monitoring and predictive AI are moving healthcare beyond generic lifestyle advice to highly personalized, precision medicine.

The conversation dives deep into the bold thesis that conditions like type 2 diabetes, obesity, and fatty liver disease are all downstream manifestations of a single, reversible metabolic dysfunction. Dr. Shah shares striking results from a recent randomized control trial, revealing how mapping an individual's unique metabolism can lead to a 71% diabetes reversal rate while dramatically reducing medication reliance. We also debate the practical challenges of continuous monitoring and unpack a timely framework for using digital platforms as a sustainable "off-ramp" for patients transitioning away from GLP-1 medications without rebound weight gain. Why might an AI coach actually be more effective (and less judgmental) than a human doctor when it comes to daily behavioral changes? 

If you’re enjoying these deep dives into the future of care delivery, be sure to subscribe to HealthTech Remedy and leave a five-star review!

Discover how Cedar uses AI to fix broken healthcare billing, automate revenue cycle management, and improve the patient financial experience.

Episode Resources:

• Cedar
• KFF Medicaid Enrollment and Unwinding Tracker
• Kora AI Agentic Voice Assistant for Patient Billing
• KFF 2024 Employer Health Benefits Survey
• Analysis of the "One Big Beautiful Bill Act" and Medicaid Impacts
• National Cancer Institute Resource on Financial Toxicity

Are we truly healing patients if we fix their health but ruin their credit? In this episode of HealthTech Remedy, we sit down with Seth Cohen, President of Cedar, to tackle the most universally dreaded part of the healthcare journey: the medical bill. You’ll discover how shifting revenue cycle management to prioritize the patient financial experience can alleviate financial toxicity while simultaneously boosting a health system's bottom line. 

As millions of Americans face the Medicaid coverage cliff and the continuous rise of high-deductible health plans, the out-of-pocket burden on patients has never been heavier. Seth breaks down how Cedar uses agentic AI to disrupt traditional billing, transforming static, confusing statements into personalized financial navigation. By leveraging large language models and virtual agents, the platform proactively connects patients with hidden resources like dormant HSAs and pharmacy co-pay assistance before a bill even drops. Tune in to find out how this targeted technology is preventing catastrophic medical debt, including a powerful patient story that proves exactly why this empathetic framework changes lives. 

If you want to stay ahead of the curve in health technology and reimbursement innovation, be sure to subscribe to HealthTech Remedy and leave us a review!

Hospitals lose millions to medical billing errors. Discover how AKASA uses AI in revenue cycle management to cut claim denials and capture lost revenue.

Episode Resources:

• Against the Rules Podcast - Six Levels Down
• AKASA Official Resource Library
• CMS Guide to MS-DRG Classifications and Logic

With hospital operating margins often sitting in the single digits, the complex maze of medical billing is silently costing health systems millions in uncollected revenue. In this episode of HealthTech Remedy, we sit down with Benjamin Beadle-Ryby, co-founder of AKASA, to explore how generative AI is fundamentally transforming revenue cycle management (RCM). You will discover how shifting from manual coding to an autonomous revenue cycle can drastically reduce claim denials, uncover missed charges, and ultimately protect a hospital's financial mission. 

The conversation unpacks the structural complexity of hospital reimbursement, where a single inpatient encounter can generate 50,000 words of documentation that human coders must manually distill into precise ICD-10 and DRG codes. Benjamin shares the framework behind AKASA’s custom large language models, revealing how fine-tuning healthcare AI on a health system's specific historical data can seamlessly surface missed quality indicators in up to 10% of claims. We also debate the delicate balance of AI automation and human oversight, questioning what happens to the highly specialized knowledge of medical billers as these tools evolve. You’ll have to listen to find out why traditional rules-based systems are failing and exactly how generative AI could drive the cost to collect below one percent by 2030. 

If you enjoyed this deep dive into the intersection of health tech and healthcare finance, please subscribe and leave a review for HealthTech Remedy.

Discover how Marathon Health is solving the primary care shortage. CEO Dr. Jeff Wells reveals how advanced primary care lowers costs and improves outcomes.

Episode Resources:

• Marathon Health Study on Advanced Primary Care ROI
• 2024 AAMC Report on Physician Shortage Projections
• News on the Marathon Health and Everside Health Merger
• Overview of the Collaborative Care Model (CoCM) for Integrated Health
• KFF 2023 Employer Health Benefits Survey

Is the traditional healthcare system failing both patients and employers? In this episode of HealthTech Remedy, we sit down with Dr. Jeff Wells, CEO and co-founder of Marathon Health, to explore how his company is radically redesigning employer-sponsored healthcare. Tune in to discover how moving away from the broken fee-for-service system can actually improve patient outcomes, increase clinician retention, and drastically reduce healthcare costs for businesses.

The hosts and Dr. Wells break down the core philosophy behind "advanced primary care," a hybrid delivery model combining on-site, near-site, and virtual clinics that meets workers exactly where they are. They examine the stark differences between traditional health systems and Marathon Health’s value-based care approach, highlighting how 30-minute appointments and seamlessly integrated behavioral health lead to a massive reduction in hospital admissions. But how exactly does this employer-driven model manage to pay for itself in year one while simultaneously solving the notorious primary care shortage? You will have to listen to find out how Marathon Health's tech-enabled infrastructure is successfully flipping the economics of population health management on its head.

If you are passionate about the future of medical delivery and health tech innovation, be sure to subscribe to HealthTech Remedy and leave us a review.

Discover how the Pittsburgh health tech ecosystem drives healthcare innovation. Leaders from UPMC and PLSA reveal the exact playbook for building AI unicorns.

Episode Resources:

• Abridge Clinical AI Platform
• UPMC Enterprises Venture Arm
• Pittsburgh Life Sciences Alliance
• Krystal Biotech Precision Therapeutics
• ElevateBio’s Biomanufacturing Expansion in Pittsburgh
• CMU Computational Biology Department

Think Silicon Valley and Boston are the only undisputed capitals of healthcare innovation? Think again. In this episode of HealthTech Remedy, we explore how Pittsburgh has quietly transformed from an industrial Rust Belt giant into a dominant powerhouse for health tech innovation and venture creation. By tuning in, you'll discover the exact blueprint this region uses to turn cutting-edge academic research into billion-dollar healthcare unicorns like Abridge, giving you a fresh perspective on where to build, scale, or invest next.

We sit down with Mary Beth Navarra-Sirio formerly of UPMC Enterprises and Megan Kahn Shaw of the Pittsburgh Life Sciences Alliance to unpack the city's highly successful approach to incubating startups. They break down the "3C perspective" framework that seamlessly bridges the gap between raw AI talent at institutions like Carnegie Mellon and real-world clinical workflows at massive, integrated health systems. You'll hear why most medical device and healthcare AI companies fail not because of flawed technology, but due to a misunderstood business model - and exactly how Pittsburgh’s full-stack commercial sandbox prevents these fatal missteps. We also reveal the two specific sectors of data-driven health and precision therapeutics that this ecosystem is betting its entire future on, but you'll have to listen to find out why.

If you're an entrepreneur or investor looking for the next massive geographic advantage in health technology, check the show notes for links to the resources and alliances mentioned today. Don't forget to subscribe to HealthTech Remedy and leave us a five-star review so we can continue bringing you the stories behind healthcare's most innovative companies.

Discover how Stedi CEO Zack Kanter built a modern healthcare clearinghouse after the Change Healthcare outage. Learn how API-driven EDI and AI transform RCM.

Episode Resources:

• Stedi
• Stedi Documentation for Healthcare EDI and APIs
• Timeline of the 2024 Change Healthcare Cyberattack
• Guide to X12 Standards and HIPAA Regulations
• CAQH Index Reports on Healthcare Transaction Costs
• About Zack Kanter: Journey and Mission

When the largest U.S. healthcare clearinghouse went dark in a massive cyberattack, it exposed the fragile, outdated plumbing powering the medical system's financial backbone. In this episode of HealthTech Remedy, we sit down with Zack Kanter, founder and CEO of Stedi, to uncover how his company is replacing decades-old billing infrastructure with modern, developer-friendly technology. By tuning in, you'll learn how upgrading the invisible layers of Electronic Data Interchange (EDI) is the crucial first step to unlocking the true potential of AI in healthcare.

Zack shares his unconventional journey from selling automotive parts to tackling the massive technical debt hidden within healthcare's revenue cycle management. He breaks down why legacy clearinghouses relying on batch processing aren't equipped for real-time APIs, and how his team built a drop-in replacement in just five days during an industry-wide crisis. The conversation also explores how seamless, automated data pipes are the missing link required for agentic AI to finally transform administrative workflows. Listen in to find out how fixing this underlying plumbing is preparing the medical system for a fully programmable future. 

If you are ready to explore the foundational technologies shaping the future of care, be sure to subscribe to HealthTech Remedy and leave us a review. Don't forget to check the show notes for more information on Zack, Stedi, and the resources mentioned in today's conversation.