Homily V of John Chrysostom's Adversus Judaeos (delivered ca. 387 CE in Antioch) continues his vehement opposition to Judaizing Christians, expressing renewed zeal to address persistent participation in Jewish practices.

Chrysostom argues that Jewish rites, once preparatory, are now obsolete and defiling after Christ's coming. He intensifies attacks on synagogues as demonic haunts and Jews as Christ-killers, urging total avoidance.

Using scriptural proofs and analogies, he portrays Judaizers as spiritually diseased, calling on the faithful to confront, admonish, and isolate them to safeguard Church purity and unity. The homily emphasizes separation and repentance amid ongoing syncretism