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What’s new in childhood asthma care—and what does it mean for everyday practice?
In this episode of Hope & Histamine: The Paediatric Allergy Podcast, we explore recent advances in paediatric asthma management, from inhaled treatments and personalised care to the evolving role of biologics in severe asthma.
We discuss key questions around asthma diagnosis, inhaler technique, treatment adherence and preventing exacerbations, alongside emerging approaches to help children achieve better asthma control.
Designed for paediatricians, GPs, nurses and other healthcare professionals caring for children with asthma, this episode brings an accessible clinical perspective to a rapidly changing field.
Source:
Dhochak, N., Robinson, P.F.M. and Saglani, S. (2026) 'Update on Pediatric asthma management: Recent advances', Pediatric Allergy and Immunology, 37, e70480. doi: 10.1111/pai.70480.
🎧 Listen now on Apple Podcasts, Spotify, Amazon Music, and YouTube
Disclaimer: The information shared in this podcast and on this website is not intended to replace professional medical advice, diagnosis, or treatment. Always consult your doctor or a qualified healthcare provider with any questions you may have about a medical condition. Please don't ignore or delay seeking medical advice based on content from this podcast or website.
Buy me a coffee: https://coff.ee/goodlifecreations
Hope & Histamine: The Paediatric Allergy Podcast brings you expert interviews, evidence-based discussions and practical clinical updates on paediatric allergy, immunology and related conditions to support healthcare professionals in everyday practice.
🎧 Listen and subscribe:
https://hopeandhistaminepodcasts.buzzsprout.com
If you enjoyed this episode, please subscribe, leave a review, and share it with colleagues to help advance the care of children with rare allergic and immunological conditions.
Send us Fan Mail
Support the show
Brought to you by - Goodlife Creations (2026).
Music by - Denys Kyshchuk from Pixabay.
How does omalizumab compare with oral immunotherapy for treating multiple food allergies? In this episode of Hope & Histamine: The Paediatric Allergy Podcast, we explore OUtMATCH Stage 2, comparing omalizumab (Xolair) with omalizumab-facilitated multi-allergen oral immunotherapy (OIT).
We unpack the findings on treatment success, allergic reactions, side effects and treatment discontinuation—and explain why tolerability matters when interpreting the results. What do these findings mean for children with peanut allergy and other food allergies, their families, and the clinicians supporting them?
Join us for an accessible, evidence-based discussion of anti-IgE therapy, food allergy desensitisation and personalised treatment decisions. Whether you’re a paediatrician, allergist, trainee or parent, discover what the OUtMATCH trial adds to the evolving conversation about multifood allergy treatment.
Sources:
🎧 Listen now on Apple Podcasts, Spotify, Amazon Music, and YouTube
Disclaimer: The information shared in this podcast and on this website is not intended to replace professional medical advice, diagnosis, or treatment. Always consult your doctor or a qualified healthcare provider with any questions you may have about a medical condition. Please don't ignore or delay seeking medical advice based on content from this podcast or website.
Buy me a coffee: https://coff.ee/goodlifecreations
Hope & Histamine: The Paediatric Allergy Podcast brings you expert interviews, evidence-based discussions and practical clinical updates on paediatric allergy, immunology and related conditions to support healthcare professionals in everyday practice.
🎧 Listen and subscribe:
https://hopeandhistaminepodcasts.buzzsprout.com
If you enjoyed this episode, please subscribe, leave a review, and share it with colleagues to help advance the care of children with rare allergic and immunological conditions.
Send us Fan Mail
Support the show
Brought to you by - Goodlife Creations (2026).
Music by - Denys Kyshchuk from Pixabay.
Can eating more eggs and peanuts during pregnancy and breastfeeding reduce a baby’s risk of developing food allergy?
In this episode of Hope & Histamine: The Paediatric Allergy Podcast, we examine the PrEggNut trial, a large randomised study involving more than 2,100 pregnant women whose babies had a strong family history of allergic disease. Researchers compared a maternal diet rich in eggs and peanuts with a standard-intake diet from pregnancy until four months after birth.
Despite greater maternal exposure, the high-intake diet did not significantly reduce egg or peanut allergy in infants at one year of age. We explore the study’s findings, its strengths and limitations, and what the results mean for maternal diet, breastfeeding and current approaches to preventing food allergy in children.
A concise, evidence-based discussion for parents, paediatricians, allergy professionals and anyone interested in pregnancy nutrition and infant allergy prevention.
Source:
Palmer, D.J., Sullivan, T.R., Campbell, D.E., Netting, M.J., McWilliam, V., Perrett, K.P., Makrides, M., et al. (2026)'Trial of a Maternal Diet Rich in Eggs and Peanuts to Reduce Infant Allergy', New England Journal of Medicine, 395(11), pp. 1090–1099. doi: 10.1056/NEJMoa2605659.
🎧 Listen now on Apple Podcasts, Spotify, Amazon Music, and YouTube
Disclaimer: The information shared in this podcast and on this website is not intended to replace professional medical advice, diagnosis, or treatment. Always consult your doctor or a qualified healthcare provider with any questions you may have about a medical condition. Please don't ignore or delay seeking medical advice based on content from this podcast or website.
Buy me a coffee: https://coff.ee/goodlifecreations
Hope & Histamine: The Paediatric Allergy Podcast brings you expert interviews, evidence-based discussions and practical clinical updates on paediatric allergy, immunology and related conditions to support healthcare professionals in everyday practice.
🎧 Listen and subscribe:
https://hopeandhistaminepodcasts.buzzsprout.com
If you enjoyed this episode, please subscribe, leave a review, and share it with colleagues to help advance the care of children with rare allergic and immunological conditions.
Send us Fan Mail
Support the show
Brought to you by - Goodlife Creations (2026).
Music by - Denys Kyshchuk from Pixabay.
What happens when a severe allergic reaction affects not only the skin and airways but also the coronary arteries?
In this episode of Hope & Histamine: The Paediatric Allergy Podcast, we explore Kounis syndrome—an acute coronary syndrome triggered by an allergic or hypersensitivity reaction. We discuss how mast-cell activation and inflammatory mediators can cause coronary artery spasm, plaque disruption or stent thrombosis, resulting in symptoms that may resemble a heart attack alongside features of anaphylaxis.
Discover the common triggers, different clinical types, warning signs, diagnostic challenges and key management considerations. This episode also examines the delicate balance involved in treating anaphylaxis and cardiac ischaemia simultaneously.
An essential listen for paediatricians, allergists, emergency clinicians, cardiologists, trainees and anyone interested in the important connection between allergy and the heart.
Sources:
🎧 Listen now on Apple Podcasts, Spotify, Amazon Music, and YouTube
Disclaimer: The information shared in this podcast and on this website is not intended to replace professional medical advice, diagnosis, or treatment. Always consult your doctor or a qualified healthcare provider with any questions you may have about a medical condition. Please don't ignore or delay seeking medical advice based on content from this podcast or website.
Buy me a coffee: https://coff.ee/goodlifecreations
Hope & Histamine: The Paediatric Allergy Podcast brings you expert interviews, evidence-based discussions and practical clinical updates on paediatric allergy, immunology and related conditions to support healthcare professionals in everyday practice.
🎧 Listen and subscribe:
https://hopeandhistaminepodcasts.buzzsprout.com
If you enjoyed this episode, please subscribe, leave a review, and share it with colleagues to help improve awareness of hereditary angioedema and advance the care of children with rare allergic and immunological conditions.
Send us Fan Mail
Support the show
Brought to you by - Goodlife Creations (2026).
Music by - Denys Kyshchuk from Pixabay.
Is it time to rethink the traditional blue reliever inhaler for children with mild asthma?
In this episode of Hope & Histamine: The Paediatric Allergy Podcast, we examine the landmark 2025 CARE trial published in The Lancet. This 52-week randomised controlled trial compared budesonide–formoterol with salbutamol as reliever therapy in children with mild asthma.
We explore whether an anti-inflammatory reliever inhaler can provide better protection than salbutamol alone, examining the trial’s findings on asthma attacks, symptom control, safety and treatment burden. We also consider what the results could mean for paediatric asthma guidelines, clinical practice and conversations with children and their families.
Whether you are a paediatrician, GP, nurse, pharmacist, trainee or parent, this episode offers a clear and clinically relevant discussion of a study that could reshape how mild childhood asthma is managed.
Listen now to discover whether budesonide–formoterol could represent the future of reliever therapy for children with mild asthma.
Source:
Hatter, L., Holliday, M., Oldfield, K., Kearns, C., Barry, T., Black, M., Bruce, P., Colman, A., Dickinson, E., Eathorne, A., Harwood, M., Hills, T., Lamb, R., Kerse, K., Krishnamoorthy, S., Martindale, J., Semprini, A., Shortt, N., McNamara, D., Byrnes, C.A., Dalziel, S.R., Bush, A., Weatherall, M. and Beasley, R., 2025.Budesonide–formoterol versus salbutamol as reliever therapy in children with mild asthma (CARE): a 52-week, open-label, multicentre, superiority, randomised controlled trial. The Lancet, 406, pp. 1473–1483. Available at: https://doi.org/10.1016/S0140-6736(25)00861-X.
🎧 Listen now on Apple Podcasts, Spotify, Amazon Music, and YouTube
Disclaimer: The information shared in this podcast and on this website is not intended to replace professional medical advice, diagnosis, or treatment. Always consult your doctor or a qualified healthcare provider with any questions you may have about a medical condition. Please don't ignore or delay seeking medical advice based on content from this podcast or website.
Buy me a coffee: https://coff.ee/goodlifecreations
Hope & Histamine: The Paediatric Allergy Podcast brings you expert interviews, evidence-based discussions and practical clinical updates on paediatric allergy, immunology and related conditions to support healthcare professionals in everyday practice.
🎧 Listen and subscribe:
https://hopeandhistaminepodcasts.buzzsprout.com
If you enjoyed this episode, please subscribe, leave a review, and share it with colleagues to help improve awareness of hereditary angioedema and advance the care of children with rare allergic and immunological conditions.
Send us Fan Mail
Support the show
Brought to you by - Goodlife Creations (2026).
Music by - Denys Kyshchuk from Pixabay.
Could a simple skin patch transform the treatment of peanut allergy in young children?
In this episode of Hope & Histamine: The Paediatric Allergy Podcast, we explore the latest evidence on epicutaneous immunotherapy (EPIT)—also known as the peanut patch—for toddlers and children with peanut allergy.
Drawing on findings from the EPITOPE and EPOPEX studies, we examine how peanut patch therapy works, its long-term effectiveness and safety, and whether it can increase the amount of peanut a child can tolerate. We also discuss its potential to reduce the risk of allergic reactions from accidental exposure to packaged foods and consider how well EPIT works in children who also have atopic conditions such as eczema, asthma and allergic rhinitis.
Can epicutaneous immunotherapy offer families meaningful protection while avoiding some of the challenges associated with oral immunotherapy? Could the peanut patch become part of routine childhood peanut allergy treatment?
Join us as we translate the emerging research into clear, practical information for parents, clinicians and everyone interested in the future of paediatric food allergy care.
Sources:
🎧 Listen now on Apple Podcasts, Spotify, Amazon Music, and YouTube
Disclaimer: The information shared in this podcast and on this website is not intended to replace professional medical advice, diagnosis, or treatment. Always consult your doctor or a qualified healthcare provider with any questions you may have about a medical condition. Please don't ignore or delay seeking medical advice based on content from this podcast or website.
Buy me a coffee: https://coff.ee/goodlifecreations
Send us Fan Mail
Support the show
Brought to you by - Goodlife Creations (2026).
Music by - Denys Kyshchuk from Pixabay.
Dupilumab has transformed the treatment of several type 2 inflammatory conditions—but how does it work, which children may benefit, and what should clinicians and families know before starting treatment?
In this episode of Hope & Histamine: The Paediatric Allergy Podcast, we explore the expanding role of dupilumab in paediatrics, including its use in atopic dermatitis (eczema), severe asthma and eosinophilic oesophagitis. We discuss how blocking interleukin-4 and interleukin-13 signalling helps control allergic inflammation, along with patient selection, administration, monitoring, potential adverse effects, and the practical considerations of biologic treatment.
Whether you are a paediatrician, allergy specialist, healthcare professional, or parent, this episode provides a clear, clinically relevant introduction to how dupilumab is reshaping the management of childhood atopic disease.
Sources:
🎧 Listen now on Apple Podcasts, Spotify, Amazon Music, and YouTube
Disclaimer: The information shared in this podcast and on this website is not intended to replace professional medical advice, diagnosis, or treatment. Always consult your doctor or a qualified healthcare provider with any questions you may have about a medical condition. Please don't ignore or delay seeking medical advice based on content from this podcast or website.
Buy me a coffee: https://coff.ee/goodlifecreations
Send us Fan Mail
Support the show
Brought to you by - Goodlife Creations (2026).
Music by - Denys Kyshchuk from Pixabay.
Hereditary angioedema (HAE) is a rare but potentially life-threatening genetic disorder that often presents during childhood, yet diagnosis is frequently delayed for many years. Early recognition and timely treatment can dramatically improve quality of life and reduce the risk of serious complications, including airway obstruction.
In this episode of Hope & Histamine: The Paediatric Allergy Podcast, we explore the latest evidence and practical approaches to diagnosing and managing paediatric hereditary angioedema (HAE). Whether you’re a paediatrician, allergy specialist, emergency clinician, trainee, nurse, or allied healthcare professional, this episode provides a comprehensive overview of this important condition.
In this episode, we discuss:
Join us as we review current guidelines, discuss real-world clinical challenges, and share practical insights to help clinicians recognise hereditary angioedema earlier and deliver evidence-based care for children and young people living with HAE.
Source:
Farkas, H. et al. (2026) 'International Guideline on the Diagnosis and Management of Pediatric Patients With Hereditary Angioedema', Allergy. Available at: https://onlinelibrary.wiley.com/doi/10.1111/all.70207. DOI: 10.1111/all.70207.
🎧 Listen now on Apple Podcasts, Spotify, Amazon Music, and YouTube
Disclaimer: The information shared in this podcast and on this website is not intended to replace professional medical advice, diagnosis, or treatment. Always consult your doctor or a qualified healthcare provider with any questions you may have about a medical condition. Please don't ignore or delay seeking medical advice based on content from this podcast or website.
Buy me a coffee: https://coff.ee/goodlifecreations
Hope & Histamine: The Paediatric Allergy Podcast brings you expert interviews, evidence-based discussions and practical clinical updates on paediatric allergy, immunology and related conditions to support healthcare professionals in everyday practice.
🎧 Listen and subscribe:
https://hopeandhistaminepodcasts.buzzsprout.com
If you enjoyed this episode, please subscribe, leave a review, and share it with colleagues to help improve awareness of hereditary angioedema and advance the care of children with rare allergic and immunological conditions.
Send us Fan Mail
Support the show
Brought to you by - Goodlife Creations (2026).
Music by - Denys Kyshchuk from Pixabay.
Why do your ears feel blocked during allergy season? Can hay fever really affect your hearing? What causes that frustrating sensation of ear fullness, popping, crackling or pressure that just won’t go away?
In this episode of Hope & Histamine: The Paediatric Allergy Podcast, we explore the important relationship between allergic disease and Eustachian Tube Dysfunction (ETD)—a common but often misunderstood condition affecting both children and adults.
Join us as we discuss:
Whether you’re a parent, patient, allergy sufferer, healthcare professional or simply curious about the connection between allergies and ear health, this episode provides clear, evidence-based guidance to help you better understand and manage Eustachian Tube Dysfunction.
Source:
Klimek, L. et al. (2025) 'Otitis Media With Effusion (OME) and Eustachian Tube Dysfunction: The Role of Allergy and Immunity—An EAACI Position Paper', Allergy. doi: 10.1111/all.16554.
🎧 Listen now on Apple Podcasts, Spotify, Amazon Music, and YouTube
Disclaimer: The information shared in this podcast and on this website is not intended to replace professional medical advice, diagnosis, or treatment. Always consult your doctor or a qualified healthcare provider with any questions you may have about a medical condition. Please don't ignore or delay seeking medical advice based on content from this podcast or website.
Buy me a coffee: https://coff.ee/goodlifecreations
Subscribe to Hope & Histamine for expert discussions on paediatric allergy, immunology and related conditions, featuring the latest research and practical advice from specialists.
🎧 Listen on your favourite podcast platform or visit:
https://hopeandhistaminepodcasts.buzzsprout.com
If you enjoy the podcast, please subscribe, leave a review and share this episode to help others learn more about allergy-related conditions.
Send us Fan Mail
Support the show
Brought to you by - Goodlife Creations (2026).
Music by - Denys Kyshchuk from Pixabay.
Orofacial Granulomatosis (OFG) is a rare but often overlooked inflammatory condition that can present with persistent lip swelling, oral ulcers, gum changes, and facial swelling. Because its symptoms overlap with many other conditions, diagnosis is frequently delayed, leaving patients and families searching for answers.
In this episode of Hope & Histamine: The Paediatric Allergy Podcast, we take a deep dive into the science and clinical management of Orofacial Granulomatosis. We discuss what OFG is, why it develops, and its important associations with Crohn’s disease, allergy, and other inflammatory disorders. You’ll learn how clinicians approach the diagnosis, the role of biopsies and investigations, and the latest evidence-based treatment options available for both children and adults.
Whether you’re a healthcare professional, medical student, patient, or parent, this episode provides a clear, practical, and evidence-based overview of this fascinating condition.
In this episode, we cover:
Join us as we separate fact from fiction and explore the latest understanding of Orofacial Granulomatosis, helping listeners recognise the condition earlier and understand the best approaches to diagnosis and management.
Sources:
🎧 Listen now on Apple Podcasts, Spotify, Amazon Music, and YouTube
Disclaimer: The information shared in this podcast and on this website is not intended to replace professional medical advice, diagnosis, or treatment. Always consult your doctor or a qualified healthcare provider with any questions you may have about a medical condition. Please don't ignore or delay seeking medical advice based on content from this podcast or website.
Buy me a coffee: https://coff.ee/goodlifecreations
🎧 Subscribe to Hope & Histamine: The Paediatric Allergy Podcast for expert discussions on paediatric allergy, immunology, and related conditions. New episodes feature practical, evidence-based insights from leading specialists, designed for clinicians, patients, and families alike.
🌐 Podcast website: https://hopeandhistaminepodcasts.buzzsprout.com
Send us Fan Mail
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Brought to you by - Goodlife Creations (2026).
Music by - Denys Kyshchuk from Pixabay.
From the publisher's feed
“Helping you understand allergies—one episode at a time”
Welcome to Hope & Histamine, the trusted podcast for families navigating the complex world of paediatric…
From eczema to food allergies, asthma to anaphylaxis, each episode breaks down medical facts into practical advice—empowering parents, caregivers, and patients with reliable information and hope.
Tune in for expert insights, real stories, and up-to-date recommendations designed to help you breathe a little easier.