Hope Lies in Dreams

Hope Lies in Dreams

By Nature BiotechnologyBusinessEntrepreneurshipScienceMedicineHealth & FitnessLife Sciences
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Hope Lies in Dreams episodes

  • Chapter 10: Dr. Crooke
    The biggest deal ⬩ In the black ⬩ End of an era ⬩ n of 1 ⬩ Small places ⬩ A life of control ⬩ The doctor will see you now

    Hosted on Acast. See acast.com/privacy for more information.

    51 min
  • Chapter 9: the last of his kind
    Award season ⬩ NURTURE, and Gabriel ⬩ Kyle Derkowski’s new future ⬩ The drugs of SMA ⬩ Piece of magic ⬩ Frank’s Super Bowl

    Hosted on Acast. See acast.com/privacy for more information.

    40 min
  • Chapter 8: part of something big
    Ethics lessons ⬩ Biogen re-ups ⬩ The ultimate sacrifice ⬩ FDA as partner ⬩ Emma’s phase 3 ⬩ Doug Kerr’s bright idea ⬩ Isis to Ionis ⬩ Spinraza approval

    Hosted on Acast. See acast.com/privacy for more information.

    43 min
  • Chapter 7: the SMA gang
    The Larsons ⬩ The skunkworks project ⬩ The most unmet need ⬩ Instant synergy ⬩ Another first for antisense ⬩ The clinic, again ⬩ The achievements of Kathie Bishop

    Hosted on Acast. See acast.com/privacy for more information.

    41 min
  • Chapter 5: valley of antisense
    The genomics bubble ⬩ Affinitak fails ⬩ Lynne saves the company ⬩ Hybridon pivots ⬩ New chemistries ⬩ Regulus formed ⬩ Isis as cult

    Hosted on Acast. See acast.com/privacy for more information.

    42 min
  • Chapter 4: three kinds of failure
    Stumbling out of the gate ⬩ Launch of Vitravene ⬩ Questions about antisense ⬩ The field thins ⬩ Clinical failure ⬩ The darkest days

    Hosted on Acast. See acast.com/privacy for more information.

    44 min
  • Chapter 3: San Diego restart
    Rosanne ⬩ An investor emerges ⬩ Founding Isis ⬩ The old garage ⬩ A proper space ⬩ A growing antisense scene ⬩ Starting a pipeline ⬩ Isis goes public

    Hosted on Acast. See acast.com/privacy for more information.

    48 min
  • Chapter 2: a winding path
    Quits Purdue ⬩ Pharmacy school ⬩ Off to Baylor ⬩ Harris Busch ⬩ Bristol Labs ⬩ SmithKline ⬩ The death of Nancy Crooke ⬩ The end of SmithKline

    Hosted on Acast. See acast.com/privacy for more information.

    47 min
  • Chapter 1: an ugly place
    Stan Crooke is born ⬩ A tenuous existence ⬩ Life with his mother ⬩ The Tech Corner ⬩ Arsenal Tech High School ⬩ Nancy ⬩ Hoodlum ways ⬩ Off to Purdue

    Hosted on Acast. See acast.com/privacy for more information.

    33 min

About Hope Lies in Dreams

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Stan Crooke rose from poverty to found a company that pioneered antisense drugs. After decades of struggle and years of public doubt, the company created a treatment that has saved thousands of…