Mark Cuban made millions off of tech startups, then billions off of stocks — and later went on to buy and revive the Dallas Mavericks. He has come to define the persona of the serial entrepreneur.

In 1968, competitors sued to keep Herb Kelleher's new airline grounded. After a 3-year court fight, the first plane took off from Dallas. Today Southwest Airlines operates nearly 4,000 flights a day.

As a kid, José Andrés tended fires for his father's backyard paella cookouts. Later, he trained with the best Spanish chefs, and began building a restaurant empire that would transform the way many Americans dine out.

L.A. Reid began his music career as a drummer. Then he co-founded LaFace Records, discovering dozens of future pop superstars. Reid is now one of the most influential executives in the music industry.

Jane Wurwand moved to Los Angeles with a suitcase and a beauty school diploma. She started what would become Dermalogica, an international beauty empire that set the standard for skin care.

Suroosh Alvi was a recovering addict when he started a scrappy underground magazine in Montreal. It grew into VICE Media — a multi-billion dollar company that has shaken up the world of journalism.

Gary Erickson asked his mom, "Can you make a cookie without butter, sugar or oil?" The result was Clif Bar, an energy bar named after his dad — now one of the most popular energy bars in the U.S.

As a kid, Cathy Hughes practiced her DJ routine while her siblings banged on the bathroom door. As an adult, she founded Radio One, the country's largest African-American owned broadcasting company.