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Ever wonder what your cat’s DNA can tell us about fetching, affection, and health? We teamed up with Dr. Elinor Karlsson, chief scientist at Darwin’s Ark and professor at UMass Chan and the Broad Institute, to unpack how a simple fur-combing kit and smart surveys can unlock big answers about everyday feline life. No lab coats at home required - just your observations, your cat’s fur, and a few minutes of thoughtful reporting.

We dig into why cats are such a powerful, understudied genetic model compared with dogs. Because most cats aren’t shaped by recent, narrow breed histories, their diversity offers cleaner signals for behavior genetics and disease research. That opens the door to questions we’ve struggled to answer: Are fetching and other elements of the predatory sequence strongly heritable? How does early socialization change adult confidence and play? Which common diseases in cats have measurable genetic risk, and which are driven by environment? 

We also confront internet myths with data. The “orange cats are dumb” trope? Not supported by early looks, and ongoing work aims to test these claims at scale. Affection comparisons with dogs? Careful measures suggest cats are just as attached as many guardians know firsthand. Best of all, Darwin’s Ark is open data, so researchers everywhere can build on these findings - and your contributions fuel that progress. If you’re ready to help, there’s a limited-time $50 sequencing offer (use code Hiss&Tell25) using a gentle fur comb, making participation easier and less stressful for cats.

Join us as we connect guardian insights with modern genomics to advance feline science. Subscribe, share this episode with a cat-loving friend, and leave a review so more people discover the project - and consider enrolling your cat at darwinsark.org with the code shared on the show. Your cat’s fur might change what we know about cats forever.