Your Genes by Design

How Your Genes Shape Digestion — And Why It Feels Different After 45


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If digestion feels different than it used to — foods sitting heavier, more bloating, stronger reactions to stress, or less tolerance for certain fibers — this episode helps explain why.

This episode explores how gut health has always been shaped by your genes, and why those patterns often become more apparent after 45 as hormonal, microbial, and digestive supports shift.

You’ll learn how:

  • Gut health is influenced by genetics 
  • Hormonal changes affect motility, microbiome balance, and digestive comfort
  • The microbiome becomes more sensitive to stress, sleep, and medications after 45
  • Key genes like FUT2, BCMO1, and ADRB2 shape food tolerance, gut lining support, and stress-related digestion
  • Simple, biology-aligned strategies can support digestion without extremes or restriction

This episode is especially helpful if you’ve noticed bloating, slower digestion, food sensitivities, stress-related gut symptoms, mixed results from probiotics after 45. Or maybe some of these patterns have always been present but feel harder to ignore now.

Visit my website at inspiredlivingforwomen.com to learn more about me and the work I do.


If you’ve ever looked at lab results and felt like they didn’t fully explain what was happening in your body, you may find this helpful.

Download the free guide When “Normal” Lab Results Don’t Feel Normal, which explains how genomics adds context to bloodwork, hormone panels, and other health tests by showing how genes influence the body’s underlying processes.

Download the guide


This podcast is for educational purposes only and is not intended to diagnose, treat, or provide medical advice. The information shared reflects general biological and genetic principles. Always consult a qualified healthcare professional regarding your own health decisions.

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Your Genes by DesignBy Lauri Wakefield