MrBeast and his team visiting and surviving five of the deadliest places on Earth. They start by spending a night in a cage surrounded by wild animals in an African safari, followed by ice climbing a frozen waterfall. Next, they drive a notoriously dangerous road in Bolivia, encounter sharks in open water, and trek through the Amazon rainforest during a flash flood. The final and deadliest location is Snake Island, where they spend a night amidst venomous snakes, even assisting scientists with snake research.