ImmunoCAST

In this episode of ImmunoCAST, hosts Gary and Luke break down the essentials of tree nut allergen components, focusing on hazelnut, cashew, walnut, and Brazil nut. They highlight the significant prevalence of tree nut allergies and the importance of accurate diagnosis using component-resolved diagnostics. The discussion covers different types of allergen components, such as PR-10 proteins, lipid transfer proteins, and storage proteins, and what they mean for patient care. This episode is designed to help primary care clinicians better understand how to predict the severity of allergic reactions and make informed decisions in managing their patients. An interpretation guide and lab ordering information are also provided to make it easy to apply these insights in practice.

Episode resources and references available at: https://www.thermofisher.com/phadia/us/en/resources/immunocast/s2e1.html?cid=0ct_3pc_05032024_9SGOV4

How can primary care clinicians optimize the diagnosis and treatment of stinging insect allergies? Tune into this episode of ImmunoCAST and hear a discussion around allergies to bee, wasp, and fire ant venoms. You’ll learn how testing with allergen components can aid in reaching an accurate diagnosis, the significance of tryptase levels in forecasting severe allergic reactions, as well as how impactful immunotherapy may be when conducted based on accurate diagnostic testing.

Episode resources and references available at https://www.thermofisher.com/phadia/us/en/resources/immunocast/s1e13.html?cid=0ct_3pc_05032024_9SGOV4

More allergenic peanuts? Fungi in crops that may make patients more susceptible to food allergy sensitization? And what does the epithelial barrier hypothesis have to do with all of it? Tune into this newsroom episode of ImmunoCAST as we discuss a recently published review paper by Ashley Sang Eun Lee, MD, and Nicole Ramsey, MD, PhD, from the Icahn School of Medicine at Mount Sinai which presents some of the interesting ways that climate change may impact patients with food allergies.

Episode resources and references available at https://www.thermofisher.com/phadia/us/en/resources/immunocast/s1e12.html?cid=0ct_3pc_05032024_9SGOV4

Ever since the CDC released its Morbidity and Mortality Weekly report about alpha-Gal syndrome (AGS) last summer, it seems that everyone is talking about this odd allergy to red meat. Whether you’re an allergist or a primary care clinician, get the clinical facts about AGS in this episode of ImmunoCAST where we explore the syndrome’s origins and discovery, what potential foods (some perhaps lesser known) and medical products may cause reactions, and the most effective way to diagnose and treat patients.

Episode resources and references available at https://www.thermofisher.com/phadia/us/en/resources/immunocast/s1e11.html?cid=0ct_3pc_05032024_9SGOV4

Can patients tolerate baked forms of egg and milk? Is it a clinical peanut allergy or cross-reactivity with pollen? In this episode of ImmunoCAST, Gary and Luke dive into food allergen components and their impact on patient management. Their discussion covers specific proteins found in eggs, milk, peanuts, and tree nuts and what it means for patients who are sensitized to them. They also discuss the role of allergen component diagnostics, how it can provide clarity, and aid in appropriate patient care decisions.

Episode resources and references available at https://www.thermofisher.com/phadia/us/en/resources/immunocast/s1e10.html?cid=0ct_3pc_05032024_9SGOV4

In this episode of ImmunoCAST, listen to a discussion around cannabis allergy and the importance of healthcare providers recognizing and inquiring about its exposure, especially in patients with asthma or food allergies. Gary and Luke delve into the history, routes of exposure, and the identification of specific allergens within cannabis, such as lipid transfer proteins, which may cross-react with other plant foods. This episode highlights the need for improved diagnostic methods and greater clinical awareness of cannabis as a potential allergen.

Episode resources and references available at https://www.thermofisher.com/phadia/us/en/resources/immunocast/s1e9.html?cid=0ct_3pc_05032024_9SGOV4

In this episode of ImmunoCAST, Gary and Luke explore the new European Academy of Allergy and Clinical Immunology (EAACI) food allergy diagnosis guidelines. They break down some of the significant recommendations found within these guidelines, such as important questions clinicians should ask during a structured food allergy history, the role of diagnostic testing, and the use of testing with allergen components in a diagnosis.

Episode resources and references available at https://www.thermofisher.com/phadia/us/en/resources/immunocast/s1e8.html?cid=0ct_3pc_05032024_9SGOV4

Is it really allergies causing patients’ rhinitis symptoms this spring or is it something nonallergic? Sure, pollen is out and about, but that doesn’t mean that those nonallergic triggers simply disappear when allergy season starts. Listen in as Gary and Luke discuss the different types of nonallergic rhinitis, potential triggers, and how healthcare providers can help provide clarity this allergy season when allergy medication isn’t working, and symptoms aren’t easing up.

Episode resources and references available at https://www.thermofisher.com/phadia/us/en/resources/immunocast/s1e7.html?cid=0ct_3pc_05032024_9SGOV4

Allergic asthma can be triggered by pollen, dust mites, pets... and thunderstorms? It's not uncommon for clinicians to see patients with respiratory allergies who also suffer from allergic asthma. Join Gary and Luke as they discuss allergic asthma as well as important clinical information, such as practice parameters and guidelines, which may help healthcare providers optimize their patient management.

Episode Resources and references available at https://www.thermofisher.com/phadia/us/en/resources/immunocast/s1e6.html?cid=0ct_3pc_05032024_9SGOV4