Dr. James Hagman discusses a 1997 paper from the laboratory of Tak Mak, 

which first described the phenotype of T and B cells in mice lacking IRF4.

[IMMUNOCAST] PILLARS OF IMMUNOLOGY

Science & Medicine

Dr. Katherine Fitzgerald discusses a 2002 paper by Jürg Tschopp and colleagues that first defined the formation of the inflammasome complex.

Dr. Claudia Kemper discusses a 1985 PNAS paper that first identified CD46, a key regulatory molecule in the complement system.

Dr. Todd Fehniger discusses two seminal papers that demonstrated a role for IL-15 in the development and survival of natural killer cells.

Dr. Alberto Martin discusses A 1985 paper demonstrating that cancer could be caused by a non-mutated version of Myc