Dr. Dr. Mark Kaplan discusses a 1989 Science paper by Gerald Crabtree that demonstrated the mechanism by which cyclosporin A inhibited T cell activation.

[IMMUNOCAST] PILLARS OF IMMUNOLOGY

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Medicine

Dr. Katherine Fitzgerald discusses a 2002 paper by Jürg Tschopp and colleagues that first defined the formation of the inflammasome complex.

Dr. Claudia Kemper discusses a 1985 PNAS paper that first identified CD46, a key regulatory molecule in the complement system.

Dr. Todd Fehniger discusses two seminal papers that demonstrated a role for IL-15 in the development and survival of natural killer cells.

Dr. Alberto Martin discusses A 1985 paper demonstrating that cancer could be caused by a non-mutated version of Myc

[IMMUNOCAST] PILLARS OF IMMUNOLOGY

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