The Cancer Letter

In the Headlines: What’s in Trump’s draft budget?


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A confidential Trump administration budget document obtained by The Cancer Letter called for a 40% budget cut to NIH and a restructuring of the 27 existing NIH institutes and centers down to just eight. But what else is in it?

In this week’s episode, Paul Goldberg, editor and publisher of The Cancer Letter, and Jacquelyn Cobb, associate editor, talk about other ways the 64-page budget document may impact cancer research. 

It seems that the cut to FDA was very small, Paul said. However, the budget would zero out the 21st Century Cures Act. 

“If that indeed happens, FDA will not be able to hire people at salaries that were never competitive anyway, but at least they were kind of getting towards competitive,” Paul said. “But compare it with the salary of a dean somewhere, and you're getting into like 30% of what somebody like that earns. So, it becomes kind of a very difficult place to go work.”

The other, more concerning potential impact of the budget? CDC’s grants for state cancer registries is nowhere to be found. 

“I am not seeing something that kind of freaks me out, which is I'm not seeing the grants for cancer registries grants to states,” Paul said. “Now, the United States has what is viewed as one of the world's greatest, if not the world's greatest, cancer statistics/cancer epidemiology/data gathering apparatuses anywhere.

“This was built since roughly about 25 years ago, when states started receiving these grants. It covers about 97% of the country. And I'm not seeing that in there. This is something that CDC operated, so what does that mean? I don't know yet. I hope to find out.”

Other stories mentioned this week include:

  • The Directors: Louis Weiner and Taofeek Owonikoko on keeping up morale amid uncertainty—“We are resolute. We are committed to continuing to move the work forward.”

  • RFK Jr. urges FDA staff to resist “agency capture” by special interests and resist “deep state”—Whistleblowers will be “honored”

  • TIL + pembro regimen achieves 24% response rate in solid epithelial tumors, marking a step forward in immunotherapy research

  • What would Mary do? Trump’s actions call for Lasker-style advocacy

A transcript of this podcast is available: https://cancerletter.com/podcastc/20250423-budget/ 

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