In the Know with Amol Sarva

The different foods we eat and how they interact make a huge difference in disease progression, weight, and everything else. Dr. Jeff Alfonsi is a practicing physician for years, and chief medical officer of RxFoods which is designed to identify what you are eating and how to get better results.

Metabolic Health is the biggest medical breakthrough of the moment. Dive in.

Let's understand an overlooked dimension of the weight loss revolution underway -- the microbes in the digestive system themselves, potentially where GLP-1s come from in the first place. Duke's gut biome expert Maya Kaelberer gives us a guide.

Metabolic Health is the biggest medical breakthrough of the moment. Dive in!

Metabolic Health is the biggest medical breakthrough of the moment

Let's understand the cellular mechanisms and some of the most promising and widely used drugs in the world with one of the foremost researchers in the field, Matt Kaeberlein, formerly of University of Washington and now founder of longevity company Optispan

Metabolic Health is the biggest medical breakthrough of the moment

Mapping all the ways the GLP-1 drugs like Ozempic do and might work means we need to understand the biome and the efficacy of surgical interventions. We talk to Professor Randy Seeley who directs University of Michigan's Nutrition Obesity Research Center

Metabolic Health is the biggest medical breakthrough of the moment

Dr. John Buse has been at the forefront of diabetes research and endocrinology since before the first GLP-1 results started to become known. He studies the body's systems that seem to be at the core of how Ozempic and diabetes operate -- let's learn about the endocrine system and map out these system-level interactions

Metabolic Health is the biggest medical breakthrough of the moment

We have one of the world's experts on the liver - the place your body stores lots of energy from food, and distributes it onward to other systems, Dr. Waj Mehal of the Yale School of Medicine.

We lay out a map of the systems in digestion and metabolism, weight loss and exercise -- plus the different pathways that GLP-1s like Ozempic are using, and what else expected or unexpected is going on in our bodies

Metabolic Health is the biggest medical breakthrough of the moment

Get up to speed on the cellular biology with a fantastic overview from PhD scientist and founder of breakthrough pharma platform Cambrian Bio