Infectious Diseases

Host: Joshua Sharfstein, MD

Host: Stephanie Desmon

Guest: Julie Messersmith

Guest: Denis Wirtz

The challenges presented by the pandemic are giving rise to a pipeline of research proposals focused on COVID-19. Julie Messersmith and Denis Wirtz are leading Johns Hopkins University's multidisciplinary research projects to develop better detection and protection tools and treatments for COVID-19 patients. They talk to Stephanie Desmon about how engineers, public health specialists, and medical doctors are teaming up to develop better testing and treatment solutions on incredibly fast-tracked timelines.

Published April 21, 2020

Host: Linda Bernstein, Pharm.D.

The Drug Enforcement Administration (DEA) issued a new guidance for the issuance of oral Schedule II prescriptions in light of the COVID-19 pandemic and nationwide public health emergency. Pharmacist Dr. Linda Bernstein details the DEA’s temporary exceptions to the regulations to ease prescribing and dispensing of these controlled substances during this challenging time.

Published April 24, 2020

Host: Linda Bernstein, Pharm.D.

The US Food and Drug Administration has authorized clinicians to prescribe chloroquine and hydroxychloroquine for hospitalized patients with COVID-19, despite warnings from scientific advisers that no randomized controlled trial has been conducted to support the drugs’ safety and efficacy in this population. Pharmacist Dr. Linda Bernstein takes us through the FDA’s decision process, the parameters of the issuance, and comments made by the experts on this emergency ruling.

Published April 24, 2020

Host: Linda Bernstein, Pharm.D.

Join pharmacist Dr. Linda Bernstein as she highlights several articles from recent literature describing coagulopathies in severely ill COVID-19 patients in China. She explores the cause and effect theories behind these findings and whether the observed coagulopathies are due directly to the virus, the critically ill condition of the patient that predisposes them to thromboembolism, or some combination of the two.

Published April 24, 2020

Host: Joshua Sharfstein, MD

Guest: Preeti N. Malani MD

Colleges and universities are already starting to think about what it would take to reopen for the fall semester. But bringing back students, faculty, and staff—and welcoming the class of 2024—will require a complete rethinking of campus life. Dr. Preeti Malani, Chief Health Officer of the University of Michigan, talks to Dr. Josh Sharfstein about how she’s considering the health and safety of 50,000 students plus faculty and staff during the COVID-19 pandemic.

Published April 20, 2020

Host: Joshua Sharfstein, MD

Guest: Tom Inglesby, MD

Does the virus cause male sterility? Are false negatives a problem with COVID tests? Is there a connection between how much virus you’re exposed to and how serious the illness is? Should people on immunosuppressive drugs stop taking them? Does the virus “reactivate?” Can people really become immune? Why are there so many more cases in the northern hemisphere? Why will a COVID-19 vaccine take so long when we come up with a new flu vaccine every year?

Tom Inglesby, Director of the Johns Hopkins Center for Health Security, answers a grab bag of listener questions.

Published April 17, 2020

Host: Joshua Sharfstein, MD

Host: Stephanie Desmon

Guest: Roni Neff

Bare shelves in grocery stores feed pandemic anxiety but Roni Neff, an expert on food systems and public health at the Johns Hopkins Center for a Livable Future, says this is not the biggest concern. Neff talks to Stephanie Desmon about how our robust food industry depends largely upon keeping its workers safe and well, how a pandemic completely shifts the model of emergency food access, and what’s being done to address these unique challenges to ensure everyone is fed.

Published April 16, 2020

Host: Joshua Sharfstein, MD

Host: Stephanie Desmon

Guest: Crystal R. Watson, DrPH

Contact tracing is a core tool of public health. Now, it could be a way to reopen the world. Crystal Watson of the Center for Health Security is the lead author of a recent report with a national plan to scale up our capability to conduct contact tracing. Watson talks to Stephanie Desmon about what contact tracing entails, how technology could help, how to approach privacy concerns, and why the plan could help employ thousands of people with some basic training.

Published April 16, 2020

Host: Joshua Sharfstein, MD

Host: Stephanie Desmon

Guest: Allison Barlow, PhD

Poor health care, lacking infrastructure, and generational poverty combine to make Native Americans especially vulnerable to COVID-19. With previous infectious respiratory illnesses like H1N1, mortality rates were sometimes four to five times higher than US averages among tribal communities. Allison Barlow, Director of the Center for American Indian Health, talks to Stephanie Desmon about COVID-19’s particular threats to Native Americans, what’s being done to help mount a “culturally informed” response, and how the virus is “revealing the cracks in our systems.”

Published April 15, 2020

Host: Joshua Sharfstein, MD

Host: Stephanie Desmon

Guest: Meghan F. Davis, PhD, DVM

Most new diseases originate from “spillover events” where humans come into contact with wild animals. Veterinarian and scientist Meghan Davis talks to Stephanie Desmon about the rise of infectious diseases and what is being done to prepare for future spillover events. She also covers how a tiger in the Bronx Zoo got a test, and the threats COVID-19 may pose to your own pets.

Published April 14, 2020