In Episode 48 of the Informonster Podcast, Charlie Harp is joined by Clinical Architecture’s UK team members Chris Gray and Alex Wren to explore how pharmacogenomics is moving from research into real-world clinical practice.

They dive into the Progress Project, a groundbreaking NHS initiative integrating genetic insights directly into clinical workflows to support safer, more personalized medication prescribing. From building the technical foundation to delivering real-time decision support at the point of care, Chris and Alex share what it takes to turn precision medicine into everyday healthcare.

Tune in to learn how the UK is advancing genomics, improving outcomes, and shaping the future of personalized care.

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Healthcare access isn’t just about availability, it’s about data. In this episode of The Informonster Podcast, Charlie Harp sits down with Sarah Matt, MD, MBA, Health Technology Strategist, and author of The Borderless Healthcare Revolution, to explore how gaps in healthcare data continue to create barriers for patients, providers, and caregivers alike.

Dr. Matt shares insights from her career spanning clinical practice, health tech startups, and large-scale healthcare transformation, unpacking how inconsistent, incomplete, and fragmented data undermines care delivery, limits the effectiveness of AI, and contributes to provider burnout. The conversation covers interoperability challenges, why “the average patient doesn’t exist,” and what it will really take to improve access without “burning down” the healthcare system.

If you’re interested in healthcare access, data quality, AI in medicine, and the future of patient-centered care, this episode offers a thoughtful and grounded perspective from someone who’s lived it from every angle.

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In Episode 46 of the Informonster Podcast, Charlie Harp sits down with John D’Amore a leading voice in healthcare informatics, data standards, and interoperability.

From his early days in decision support to building and selling a data normalization company, John shares the experiences that shaped his career and the lessons he’s learned along the way. Together, Charlie and John dig into the evolution of interoperability, why data quality matters more than ever, and how standards like IPS and CCDA continue to influence care delivery across the globe.

They also explore the intersection of AI and data quality, the realities of modern EHRs, and why the next generation of informatics professionals will shape the future of healthcare. John also weighs in on the growing momentum behind the Patient Information Quality Improvement (PIQI) Framework and why establishing a shared, consistent approach to measuring data quality is critical for the industry. 

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In Episode 45 of The Informonster Podcast, host Charlie Harp sits down with Ryan Howells, Principal at Leavitt Partners, to explore how collaboration, policy, and open standards are driving meaningful innovation in healthcare.

From the origins of the “Kill the Clipboard” initiative to the push for better data quality, Ryan shares how he and his team at Leavitt Partners are helping align government and industry leaders to improve the quality and usability of health data exchange. The conversation dives into digital quality measures, the evolution of HIPAA, and why an abundance mindset could be the key to transforming healthcare data exchange.

If you’re passionate about healthcare policy, interoperability, or the future of data-driven care, this episode is a must-listen.

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In this episode of the Informonster Podcast, Charlie Harp is joined by Sarah DeSilvey, DNP, FNP-C, Co-founder and Director of Terminology for the Gravity Project, to discuss the evolution of data standards supporting social determinants of health (SDOH). Together, they explore how Gravity’s collaborative work within HL7 is helping define and standardize social care data to improve interoperability and care coordination.

Sarah shares insights into the project’s origins, its impact on initiatives like USCDI and quality measurement, and the critical role of consensus-based data development. The conversation highlights how advancing SDOH data standards not only strengthens health data quality but also enables more equitable, person-centered care.

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In this episode of the Informonster Podcast, Charlie Harp takes on a new kind of guest, ChatGPT, to explore the evolving role of artificial intelligence in healthcare. 

Together, they discuss how generative AI is shaping clinical workflows, where it adds value, and where human oversight remains essential.

The conversation covers topics from bias and data quality to the ethical guardrails needed to keep AI trustworthy. 

Charlie also reflects on how tools like ChatGPT can accelerate progress while highlighting why high-quality data and human expertise will always be at the heart of meaningful innovation.

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In this episode of the Informonster Podcast, Charlie Harp sits down with healthcare IT rockstar Susan Clark for a candid conversation on the evolving world of healthcare policy. From the incentives that drive real change, to the challenges of interoperability, data quality, and patient identity, Susan shares her insights on what it takes to align policy with purpose.

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In this episode of the Informonster Podcast, Charlie Harp shares updates on the PIQI Framework and his experience at the HL7 Connectathon. He highlights progress across newly formed PIQI Alliance work groups, from claims and explanation of benefits to USCDI and quality measures like eCQMs and HEDIS. He also talks about new SAM developments, including detection and noise, and how community feedback is shaping PIQI’s evolution to strengthen healthcare data quality.

Charlie also reflects on his first Connectathon, where PIQI sparked engaging discussions and valuable feedback from across the HL7 community. The experience underscored the collaborative spirit and shared commitment to advancing data quality in healthcare.

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Joerg Schwarz, Senior Director, Global Industry Strategy & Solutions, Healthcare Data & Interoperability of Infor joins Charlie Harp to explore the future of healthcare data. They unpack how AI is raising the bar for interoperability, why data quality can’t be an afterthought, and how the PIQI Alliance is bringing the industry together to drive meaningful change. From FHIR adoption to scalable innovation, Joerg shares real-world insight into where healthcare data needs to go next. 

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In this episode of the Informonster Podcast, Clinical Architecture CEO Charlie Harp hands over the mic to our VP of Marketing, Jaime Lira, for a conversation about the evolution of the PIQI Framework. From its early beginnings as a taxonomy to its growing momentum across the industry, Charlie shares how PIQI has progressed, what’s coming next for the PIQI Alliance, and why standardizing patient data quality is more important than ever. 

• Join the PIQI Alliance or stay up to date with all things PIQI here. 
• Watch Charlie Harp and Ryan Howells, Principal at Leavitt Partners, during ViVE 2025 for their session, Measuring Patient Data Quality with PIQI.
• Read Kill The Clipboard! From Leavitt Partners

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