Dr. Sherrill R. Brown was born in Rancho Cordova, California, and raised by her single mother who worked full time as an Echocardiogram Technician at Kaiser Permanente Morse Hospital in Sacramento, California. She attended American River College for her first two years of college and then transferred to the University of California, Davis where she received her Bachelor in Science degree in Biochemistry. 

Dr. Brown worked as a Reuse Technician for DaVita during a gap year between college and medical school where she learned more about the complex challenges patients face in accessing hemodialysis. She received her medical degree from the New York Medical College in Valhalla New York in 2008 and completed her internal medicine residency training at the University of California, Davis Medical Center where she began her scholarly work in infection prevention. She worked as a Hospitalist at the University of California, Los Angeles (UCLA) before completing an Infectious Disease Fellowship in the Cedars Sinai/UCLA Combined Infectious Disease Program. After fellowship, she worked at Kaiser Permanente Woodland Hills and then the UC Davis Medical Center and Veteran Affairs Northern California Health System caring for patients with HIV at One Community Health Center while working in the areas of infection prevention, and antibiotic stewardship. She currently serves as the Site Medical Director of the Pico Passons Clinic in Pico Rivera and the Medical Director of Infection Prevention at AltaMed.

She is the proud mother of Alianna and Fabian and is married to Dr. Efrain Talamantes.