In two Texas counties along the border with Mexico, 20 to 25 percent of seniors have Alzheimer's or related dementias. Those rates are among the highest in the US and represent a mostly Latino population. But Latinos are underrepresented in Alzheimer's clinical trials. Physician and neurologist Dr. Gladys Maestre is changing that at her NIH-funded Alzheimer's research center in the Rio Grande Valley, the first of its kind in Texas. She's using a "place-based" approach to dementia care, bringing her Latina identity and cultural knowledge to investigate the social, environmental, and biological factors that influence brain health.