Irish Thoracic Society Podcast Productions

Irish Thoracic Society Podcast Productions

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Irish Thoracic Society Podcast Productions episodes

  • Scalable models of care—comparing home and hospital-based approaches to diagnosis and management with Professor Eddie Maloney

    This episode looks at obstructive sleep apnea and why diagnosis and management need scalable models of care. Professor Eddie Maloney speaks about how home sleep studies, hospital-based polysomnography, smartwatches, and remote pathways fit together in real clinical practice. The discussion includes when home testing is enough, when a full sleep lab study is still needed, and how treatment is evolving beyond CPAP to include positional devices, mandibular advancement devices, weight loss therapies, and future oral agents.


    In This Episode

    - The clinical definition of obstructive sleep apnea and why its true prevalence is likely substantially underrecognised

    - The key symptom profile and collateral history that should raise pre-test probability, including snoring, witnessed apneas, daytime sleepiness, nocturnal choking, and drowsy driving

    - Where home sleep testing is appropriate, and why a negative result does not always exclude OSA when clinical suspicion remains high

    - The limitations of home studies versus in-laboratory polysomnography for assessing sleep architecture, complex comorbidity, central sleep apnea, and non-respiratory sleep disorders

    - The evolving treatment landscape, including CPAP, positional therapy, mandibular advancement devices, hypoglossal nerve stimulation, and emerging obesity-targeted therapies

    - The move toward scalable, remote, and AI-supported sleep care pathways, with ongoing emphasis on adherence monitoring and individualized follow-up


    Guest:

    Professor Eddie Moloney is a Consultant Respiratory and Sleep Physician at Tallaght University Hospital and Beacon Hospital, with over 20 years’ experience in respiratory, sleep and general internal medicine. He has held senior clinical and leadership roles in Ireland and the UK, including as current president of the Irish Thoracic Society and has made significant contributions to respiratory and sleep medicine through research, education and professional leadership.

    Outside of medicine, Eddie is a passionate tennis player and advocate for an active lifestyle.


    Hosts:

    Dr Margaret Higgins is a third year respiratory trainee at the Mater Hospital. A graduate of University College Dublin, she is currently completing a Masters at University College Cork. She is the current ITS education co-officer with a keen interest in Medical Education. Her research interests include Pulmonary Hypertension and Interstitial Lung Disease. 


    Dr Sandra Green is an Irish-trained respiratory fellow with a strong track record in climate advocacy and multidisciplinary sustainable initiatives, as co-founder of Irish Doctors for the Environment. She has an MSc in Leadership and Innovation in Healthcare at the Royal College of Surgeons Ireland (2023–2025). With Marisssa, she co-founded the Irish Thoracic Society Podcast Productions, launching the platform in 2024 to share knowledge, insights, and innovations in respiratory care.

    LinkdIn - linkedin.com/in/dr-sandra-green-2a9536199


    Chapters

    00:00 - Welcome to Breathwork and why respiratory updates matter

    00:34 - Introducing Professor Eddie Maloney and the focus on scalable OSA care

    01:03 - Rapid-fire round

    02:57 – The definition of obstructive sleep apnea

    03:22 - How common OSA is globally and in Ireland

    03:51 - Typical symptoms and how patients get referred

    05:19 - Why so many cases remain undiagnosed

    06:55 - What smartwatches can and cannot do yet

    08:51 - Why a negative home study does not always rule out OSA

    09:45 - Key history points, including bed partner collateral

    10:40 - Home testing versus hospital sleep lab investigations

    12:05 - When to bring patients in for full polysomnography

    13:02 - What patients wear during in-lab sleep studies

    14:01 - Peripheral arterial tonometry and WatchPAT-style testing

    15:21 - How sleep data are interpreted in the home setting

    16:16 - The problem of making lifelong decisions from a one-night study

    17:39 - Remote referral, diagnosis, treatment, and follow-up pathways

    18:36 - TALA pathway setup and questionnaire-based triage

    19:28 - CPAP as the main treatment and virtual follow-up

    20:26 - AI and the future of sleep study interpretation

    20:55 - Treatment options beyond CPAP

    22:20 - GLP-1 and GIP therapies and the SURMOUNT trial results

    23:43 - When to repeat a study after significant weight loss

    25:10 - How mandibular advancement devices work

    26:14 - What personalised treatment means in sleep apnea

    27:06 - Explaining the diagnosis with patient-friendly resources

    27:47 - Improving CPAP adherence in practice

    28:43 - Traffic-light monitoring for CPAP compliance

    29:38 - How pressure settings and mask choice affect tolerance

    30:56 - Device lifespan and replacing masks and tubing

    31:26 - Follow-up schedules for stable patients

    32:20 - Sustainability and recycling of CPAP devices

    33:18 - Final take-home message and society meeting reminder


    Resources & Links:

    https://irishthoracicsociety.com/asm-2026/ Irish Thoracic Society ASM 19 th & 20 th November: Abstract Deadline 1 st September 2026, Case study forum deadline 18th September 2026

    Irish Sleep Society https://irishsleepsociety.ie/

    American Academy of Sleep https://aasm.org/clinical-resources/patient-info/


    References:

    - Malhotra A, Grunstein RR, Fietze I, et al.; SURMOUNT-OSA Investigators. Tirzepatide for the Treatment of Obstructive Sleep Apnea and Obesity. New England Journal of Medicine. 2024;391(13):1193–1205.

    doi:10.1056/NEJMoa2404881. PMID: 38912654.


    - Ryan S, Keane S, Nolan G, Purcell E, Cormican L, Irish Sleep Society

    Committee. Practice Guidelines for Standards of Adult Sleep Medicine

    Services. Irish Medical Journal. 2018;111(3):721.

    33 min
  • Inspire: Professor Eddie Maloney on building a respiratory career, leading the Irish Thoracic Society, and staying active

    In this episode Professor Eddie Maloney, consultant respiratory and sleep physician and President of the Irish Thoracic Society speaks about the career path that led him into respiratory medicine. They discuss fellowships, intensive care exposure, society leadership, advocacy priorities, and why tennis and regular exercise have been a constant throughout his working life.


    In This Episode

    - A career path through respiratory and sleep medicine, with training and leadership experience across Ireland and the UK.

    - The appeal of respiratory medicine as a specialty that combines acute care, chronic disease management, procedures, physiology, and imaging.

    - The value of fellowships and international experience in strengthening clinical judgement, adaptability, and problem-solving.

    - The role of the Irish Thoracic Society in supporting professional development, membership growth, and annual scientific meetings.

    - Current advocacy priorities in respiratory health, including air quality, climate- related impacts, vaping, and World Lung Day.

    - Practical advice for trainees on publications, case reports, and building an academic profile alongside clinical work.


    Guest

    Professor Eddie Moloney is a Consultant Respiratory and Sleep Physician at Tallaght University Hospital and Beacon Hospital, with over 20 years’ experience in respiratory, sleep and general internal medicine. He has held senior clinical and leadership roles in Ireland and the UK, including as current president of the Irish Thoracic Society and has made significant contributions to respiratory and sleep medicine through research, education and professional leadership. Outside of medicine, Eddie is a passionate tennis player and advocate for an active lifestyle.


    Hosts:

    Dr Margaret Higgins is a third year respiratory trainee at the Mater Hospital. A graduate of University College Dublin, she is currently completing a Master's at University College Cork. She is the current ITS education co-officer with a keen interest in Medical Education. Her research interests include Pulmonary Hypertension and Interstitial Lung Disease. 


    Dr Sandra Green is an Irish-trained respiratory fellow with a strong track record in climate advocacy and multidisciplinary sustainable initiatives, as co-founder of Irish Doctors for the Environment. She has an MSc in Leadership and Innovation in Healthcare at the Royal College of Surgeons Ireland (2023–2025). With Marisssa, she co-founded the Irish Thoracic Society Podcast Productions, launching the platform in 2024 to share knowledge, insights, and innovations in respiratory care.


    Linkedin: linkedin.com/in/dr-sandra-green-2a9536199


    Chapters

    00:00 - Welcome to Inspire and what the podcast aims to cover

    00:57 - Professor Eddie Maloney’s clinical background and leadership roles

    02:23 - How respiratory medicine became the right fit

    03:49 - Intensive care exposure and the Brompton fellowship

    05:35 - Why a fellowship abroad can change the way you think

    06:34 - Whether fellowships still matter for trainees today

    07:27 - Why he joined the Irish Thoracic Society

    08:48 - How the society’s committee pathway works

    09:35 - Growing membership across the respiratory MDT

    10:29 - Respiratory Health of the Nation and the annual scientific meeting

    12:20 - Current advocacy priorities: air quality, vaping, and World Lung Day

    14:09 - Tennis, fitness, and staying active through a busy career

    15:33 - Fitting exercise into early starts and full clinical days

    16:26 - Publication advice for trainees and early career doctors

    18:21 - Why finishing papers and handling review matters

    19:14 - Case reports as a practical starting point for research

    20:02 - Closing remarks and the next episode topic

    Resources and Links:

    - Irish Thoracic Society https://irishthoracicsociety.com/

    - Respiratory Health of the Nation report 2018

    https://irishthoracicsociety.com/respiratory-health-of-the-nation-2018/

    21 min
  • Inspire (Part 4) Mastering Medical Meetings: Strategies for Effective Communication and Leadership with Sarah Geraghty

    This episode features insights from healthcare communication expert Sarah Geraghty, who shares proven frameworks and practical tips on crafting clear agendas, managing time effectively, and delivering purposeful meetings. Her insights help professionals across sectors elevate their meetings to be most effective. If you’re committed to making your meetings matter—or simply want to reclaim time, reduce stress, and foster a culture of clarity—this episode is essential listening.


    In this episode:

    The crucial role of purpose and clear objectives for every gathering

    How to craft and circulate agendas in advance to prep participants effectively

    Strategies for keeping meetings on track—even when personalities and time pressures threaten to derail progress

    Techniques to empower less confident voices and build inclusive, psychologically safe environments

    The importance of ending with clear actions, owners, and timelines—so nothing slips through the cracks


    Guest

    Sarah Geraghty is Head of Careers at the Communications Clinics, specialising in preparing for high-stakes interviews and career transitions. A seasoned communication trainer and coach, she combines practical storytelling and leadership development to help candidates articulate their value. With a rich background in journalism and editorial work—including contributions to the Irish Times and The Journal, and experience as Assistant Editor of Gloss Magazine—she brings real-world insight into how healthcare professionals can perform under pressure.


    Hosts

    Marissa O’Callaghan is an Irish trained Respiratory fellow currently undertaking a post-doc fellow working in Erasmus MC Rotterdam in the Netherlands. She finished her Irish respiratory and Internal medicine training and Phd in 2025. Her areas of interest are interstitial and rare lung diseases. She enjoys clinical research, Med Ed, and dreaming up new medical innovations. Together with cohost Sandra Green, she founded the ITS podcast series in June 2024.


    Sandra Green is an Irish-trained respiratory doctor with a strong track record in climate advocacy and multidisciplinary sustainable initiatives, as co-founder of Irish Doctors for the Environment. She has an MSc in Leadership and Innovation in Healthcare at the Royal College of Surgeons Ireland (2023–2025. With Marisssa, she co-founded the Irish Thoracic Society Podcast Productions, launching a platform in 2024 to share knowledge, insights, and innovations in respiratory care.


    Chapters

    0:04 Introduction to Breathwork

    0:37 Importance of Meetings in Healthcare

    1:06 Effective Meeting Communication

    1:28 Rapid Fire Tips for Meetings

    1:56 Listening vs. Speaking in Meetings

    2:25 Purpose and Objectives of Meetings

    3:41 Structured vs. Informal Meetings

    5:32 Role of the Chair in Meetings

    7:28 Time Management in Meetings

    9:48 Encouraging Participation

    11:43 Setting the Meeting Culture

    13:29 Challenges of Meeting Overruns

    15:24 Engaging Junior Members

    17:41 Psychological Safety in Meetings

    19:37 Final Tips for Effective Meetings

    26:37 Closing and Future Plans

    27:26 Credits and Contact Information


    Resources & Links:

    Sarah Geraghty - LinkedIn https://ie.linkedin.com/in/sarah-geraghty-comms

    The Communication Clinic https://www.communicationsclinic.ie/

    28 min
  • Inspire (Part 3) From Inbox Chaos to Clarity – Smarter Email Communication in Healthcare with Sarah Geraghty

    In this episode, communication expert Sarah Geraghty uncovers the hidden impact of email habits on healthcare efficiency and patient safety. Discover how precise, purpose-driven emails can save time, reduce stress, and enhance collaboration. Learn practical strategies like the ‘BLUF’ framework and effective subject line structuring to transform your inbox chaos into streamlined communication. Perfect for clinicians and administrators eager to improve their email etiquette and workflow.


    In this episode:

    The ‘BLUF’ (Bottom Line Up Front) framework that ensures your emails are clear and effective, no matter the audience

    How to structure subject lines and content for maximum impact—without coming across as too formal or too casual

    The essential mindset shift: treating emails as strategic tools that require dedicated focus, not ongoing background noise

    Practical methods to manage post-holiday inboxes, follow-ups, and group emails

    The environmental and legal considerations around storing and sending emails—and why fewer, more meaningful messages are better for everyone


    Guest

    Sarah Geraghty is Head of Careers at the Communications Clinics, specialising in preparing for high-stakes interviews and career transitions. A seasoned communication trainer and coach, she combines practical storytelling and leadership development to help candidates articulate their value. With a rich background in journalism and editorial work—including contributions to the Irish Times and The Journal, and experience as Assistant Editor of Gloss Magazine—she brings real- world insight into how healthcare professionals can perform under pressure.


    Hosts

    Marissa O’Callaghan is an Irish trained Respiratory fellow currently undertaking a post-doc fellow working in Erasmus MC Rotterdam in the Netherlands. She finished her Irish respiratory and Internal medicine training and Phd in 2025. Her areas of interest are interstitial and rare lung diseases. She enjoys clinical research, Med Ed, and dreaming up new medical innovations. Together with cohost Sandra Green, she founded the ITS podcast series in June 2024.


    Sandra Green is an Irish-trained respiratory doctor with a strong track record in climate advocacy and multidisciplinary sustainable initiatives, as co-founder of Irish Doctors for the Environment. She has an MSc in Leadership and Innovation in Healthcare at the Royal College of Surgeons Ireland (2023–2025. With Marisssa, she co-founded the Irish Thoracic Society Podcast Productions, launching a platform in 2024 to share knowledge, insights, and innovations in respiratory care.



    Chapters

    00:00 – Introduction: Overview of email's role in healthcare

    00:28 – Email Overload: The impact of email volume on clinicians
    01:21 – Communication Challenges: How poor email practices affect patient safety
    01:50 – Rapid Fire Tips: Quick advice on email efficiency
    02:42 – When to Call: Choosing between email and phone communication
    03:10 – Post-Holiday Inbox: Strategies for managing a full inbox
    04:22 – Email Anxiety: Dealing with email-related stress
    06:37 – Global Email Statistics: The scale of email communication worldwide
    07:31 – Why Emails Matter: The importance of email in healthcare
    08:57 – Effective Use: Making emails impactful and efficient
    09:54 – Miscommunication Risks: How misunderstandings affect patient care
    10:52 – Managing Tasks: Balancing email with other responsibilities
    12:12 – Dedicated Email Time: Setting aside time for email management
    14:21 – Email Length: Finding the right balance between brevity and detail
    17:11 – BLUF Framework: Using the Bottom Line Up Front approach
    19:33 – Subject Lines: Writing effective email subjects
    21:20 – Tone and Formality: Maintaining the right tone in emails
    25:09 – CC Challenges: Managing CC chains effectively
    29:17 – Follow-Up Emails: Best practices for follow-ups
    32:59 – Email Storage: Challenges of storing emails in healthcare
    35:21 – Environmental Impact: The carbon footprint of email
    37:58 – Conclusion: Key takeaways


    Resources & Links

    Sarah Geraghty (LinkedIn): https://ie.linkedin.com/in/sarah-geraghty-comms

    The Communication Clinic: https://www.communicationsclinic.ie/
    Richard Saul Wurman's Information Anxiety (1989). New York: Doubleday.
    Nordrum, O.L. and Malone, C. (2022). "The Carbon Footprint of Digital Communication Within the Healthcare Service." Irish Medical Journal, 115(8), p. 663. Available: https://imj.ie/wp-content/uploads/2022/09/The-Carbon-Footprint-of-Digital-Communication-Within-the-Healthcare-Service.pdf (accessed 7 June 2026).

    39 min
  • Breathwork: A Career in Cystic Fibrosis with Professor Edward McKone

    In this episode, with Professor Edward McKone, we dive deep into the essentials of cystic fibrosis, exploring its underlying mechanisms, diagnostic challenges, and the revolutionary impact of CFTR modulators. Led by expert insights, this discussion highlights how evolving treatments are transforming patient outcomes and what lies ahead in CF care.

    In this episode

    - The genetics and pathophysiology of CF, including CFTR function and the impact on lungs and other organs

    - Advances in diagnosis, especially the role of newborn screening, sweat tests, and genetic sequencing

    - How CFTR modulators are changing the management landscape and their long-term effects

    - The future of CF treatment: reducing treatment burden and personalised medicine

    - The importance of holistic, multidisciplinary care and transition from paediatric to adult services

    Guest

    Professor Edward McKone is a leading respiratory physician and clinical professor based in Dublin, specialising in cystic fibrosis and respiratory disease. As a Consultant at St. Vincent’s University Hospital, he works at Ireland’s National Referral Centre for Adult Cystic Fibrosis, combining frontline care with clinical trials research. He has played a pivotal role in advancing cystic fibrosis treatment both in Ireland and internationally, including leadership roles with the Cystic Fibrosis Registry of Ireland and the European CF Registry. Alongside his clinical and research work, Professor McKone is deeply committed to medical education, currently serving as Dean of the Institute of Medicine and Co-Director of the Irish Clinician Educator Track.


    Hosts

    Dr Barry Harnedy is a respiratory specialist trainee in Ireland. He graduated from National University of Ireland Galway. He is the current Irish Thoracic Society co Educational Officer. He is passionate about digital innovation and airways assessment.


    Sandra Green is an Irish-trained respiratory fellow with a strong track record in climate advocacy and multidisciplinary sustainable initiatives, as co-founder of Irish Doctors for the Environment. She has an MSc in Leadership and Innovation in Healthcare at the Royal College of Surgeons Ireland (2023–2025). With Marisssa, she co-founded the Irish Thoracic Society Podcast Productions, launching the platform in 2024 to share knowledge, insights, and innovations in respiratory care.

    LinkdIn - linkedin.com/in/dr-sandra-green-2a9536199

    Chapters

    0:00 - Introduction

    0:30 - Rapid Fire Round on cystic fibrosis.

    6:02 - Cystic Fibrosis Pathophysiology

    9:20 - Discussion on newborn screening and diagnostic steps.

    11: 42 - Sweat test procedure

    13:37 - Milder cases in adulthood and associated symptoms.

    15:29 - CF in non-Caucasian populations and genetic testing.

    17:25 - Referral to CF Centres

    18.25 – Transition from Paediatric to Adult Care

    22:13 - Overview of the mainstays of management and treatment within CF.

    26:16 - Impact of CFTR Modulators

    31:28 - The future challenges and management of aging CF patients.

    38:57 - How socioeconomic status impacts CF outcomes in the era of modulators.

    41:43 - Key message for clinicians and patients.

    42:56 - Episode wrap-up and acknowledgments.


    Resource Links

    1. Irish Cystic Fibrosis Society Website

    2. Newborn Screening Information

    3. Cystic Fibrosis Foundation

    4. European Cystic Fibrosis Society

    5. Genetic Testing for CF

    6. CFTR Modulators Information

    7. Transitioning from Pediatric to Adult Care

    44 min
  • Inspire: A Career in Cystic Fibrosis: From Registry Data to Transformative Therapies with Professor Edward McKone (Part 1)

    In this episode of Inspire, we are joined by Professor Edward McKone, Consultant Respiratory Physician at St. Vincent’s University Hospital and a leading figure in cystic fibrosis care. Drawing on his experience of clinical medicine, research, and leadership, he reflects on the evolution of CF management and the breakthroughs that have transformed patient outcomes. Alongside this, he shares insights from a dynamic career spanning clinical medicine, clinical trials, and the advancement of medical education.


    In this episode:

    Discover Professor McKone's path to specialising in respiratory medicine and cystic fibrosis.

    Explore the role of registries in improving patient outcomes and advancing standards.

    Learn about the challenges and successes in advocating for cystic fibrosis treatments.

    Understand the importance of medical education and the development of the Irish Clinical Educator Training program.

    Gain insights into the future of postgraduate medical training in Ireland.

    Hear Professor McKone's reflections on his career and advice for aspiring medical professionals.


    Guest:

    Professor Edward McKone is a leading respiratory physician and clinical professor based in Dublin, specialising in cystic fibrosis and respiratory disease. As a Consultant at St. Vincent’s University Hospital, he works at Ireland’s National Referral Centre for Adult Cystic Fibrosis, combining frontline care with clinical trials research.

    He has played a pivotal role in advancing cystic fibrosis treatment both in Ireland and internationally, including leadership roles with the Cystic Fibrosis Registry of Ireland and the European CF Registry. Alongside his clinical and research work, Professor McKone is deeply committed to medical education, currently serving as Dean of the Institute of Medicine and Co-Director of the Irish Clinician Educator Track.


    Hosts:

    Dr Barry Harnedy is a respiratory specialist trainee in Ireland. He graduated from National University of Ireland Galway. He is the current Irish Thoracic Society co Educational Officer. He is passionate about digital innovation and airways assessment.


    Sandra Green is an Irish-trained respiratory fellow with a strong track record in climate advocacy and multidisciplinary sustainable initiatives, as co-founder of Irish Doctors for the Environment. She has an MSc in Leadership and Innovation in Healthcare at the Royal College of Surgeons Ireland (2023–2025). With Marisssa, she co-founded the Irish Thoracic Society Podcast Productions, launching the platform in 2024 to share knowledge, insights, and innovations in respiratory care.

    LinkdIn linkedin.com/in/dr-sandra-green-2a9536199


    Chapters

    00:00 – Intro & Guest Overview Overview of CF episode and Professor McKone’s background

    02:15 – The Night That Changed a Career First on-call experience → choosing respiratory medicine

    05:30 – Accidental Entry into Cystic FibrosisFrom “not knowing CF” to lifelong focus

    09:00 – Medical Education & Leadership Pathways Role of National Specialty Director & training structures

    11:30 – Rethinking Postgraduate Training in IrelandChallenges in BST → move toward broader exposure

    17:00 – Building the Clinician-Educator (ICET Programme) Why medical education needs formal training pathways

    23:00 – The Power of Registries From epidemiology → benchmarking → pharmacovigilance

    27:30 – Registries as Regulatory Tools Landmark shift: EMA recognising CF registries for Phase IV studies

    30:00 – How to Build a Registry (Practical Insights) Buy-in, minimal datasets, sustainability

    32:15 – CFTR Modulators: Cost vs Value Clinical promise vs health economics reality

    33:30 – The Sweat Chloride Moment (Key Turning Point) Why modulators changed everything

    34:50 – Career Advice and reflections Career advice: focus, mentorship, and collaboration

    36:30 – Closing Reflections


    References:

    O’Connor A. OPTIMISE: Optimisation and Progression of Training in Internal Medicine – In Search of Excellence (Interim Report). Dublin: Royal College of Physicians of Ireland; 2023.

    Corey M, McLaughlin FJ, Williams M, Levison H. A comparison of survival, growth, and pulmonary function in patients with cystic fibrosis in Boston and Toronto. J Clin Epidemiol. 1988;41(6):583-91. doi: 10.1016/0895-4356(88)90063-7. PMID: 3260274.

    Ramsey, B. W., et al. (1999). Intermittent administration of inhaled tobramycin in patients with cystic fibrosis. New England Journal of Medicine.

    36 min
  • PulmPeeps / Irish Thoracic Society collaboration: Understanding Refractory Chronic Cough: Insights from Experts

    In this episode, we explore the complex and often overlooked world of refractory chronic cough—a condition that can significantly impact patients’ quality of life, yet is frequently misunderstood or underdiagnosed. Featuring insights from leading respiratory specialists in Ireland and the United States, we examine the latest approaches to diagnosis, management, and emerging treatments aimed at improving patient outcomes and supporting clinicians in navigating this challenging area of respiratory medicine.

    Our guests, Professor Lorcan McGarvey and Professor Brendan Canning—both internationally recognised leaders in respiratory medicine and cough research—share their expertise on the neurobiology of chronic cough, the substantial morbidity experienced by patients, and strategies for more effective diagnostic investigation. We also discuss current treatment options and promising therapies on the horizon, as chronic cough increasingly gains recognition as a disease in its own right rather than merely a symptom. Whether you are a clinician, researcher, or simply interested in advances in respiratory medicine, this episode offers valuable insights into a condition that is finally receiving the attention it deserves.

    --

    Guests

    Professor Lorcan McGarvey

    Professor of Respiratory Medicine at the University of Belfast, with a focus on the neurobiology of cough. His research has significantly advanced understanding of cough hypersensitivity syndrome and contributed to the development of new therapeutic strategies. He is widely respected for his collaborative work and dedication to improving respiratory health.

    Professor Brendan Canning

    Distinguished researcher at Johns Hopkins University, specialising in the mechanisms of cough and airway diseases. His pioneering studies on neural pathways and receptor targets have helped pave the way for novel treatments in refractory chronic cough. He is recognised as a key figure in efforts to redefine chronic cough management.

    Hosts
    Dr Marissa O’Callaghan
    Irish-trained respiratory fellow currently undertaking a postdoctoral fellowship at Erasmus MC Rotterdam in the Netherlands. She completed her training in Respiratory and Internal Medicine, along with her PhD, in 2025. Her interests include interstitial and rare lung diseases, as well as clinical research, medical education, and innovation. She co-founded the ITS Podcast Series in June 2024 alongside Sandra Green.


    Dr Sandra Green

    Irish-trained respiratory fellow with a strong background in climate advocacy and multidisciplinary sustainability initiatives. She is co-founder of Irish Doctors for the Environment and completed an MSc in Leadership and Innovation in Healthcare at the Royal College of Surgeons in Ireland (2023–2025). Alongside Marissa O’Callaghan, she co-founded Irish Thoracic Society Podcast Productions in 2024 to share knowledge and innovation in respiratory care.

    57 min
  • Breathwork: Alpha-1 Antitrypsin Deficiency: Insights from Professor Gerry McElvaney (Part 2)

    This episode explores Alpha-1 Antitrypsin Deficiency, focusing on diagnosis, pathophysiology, and evolving treatments. Professor Gerry McElvaney discusses prevalence in Ireland, the impact on lung and liver disease, and why early detection significantly improves outcomes.


    Key topics include:


    Prevalence and genotypes (ZZ, MZ, SZ)

    Lung and liver disease, plus manifestations like panniculitis and vasculitis

    Diagnostic challenges: levels vs genotype/phenotype and need for multimodal testing

    Importance of early detection, smoking cessation, and targeted intervention

    Emerging therapies: RNA editing, gene silencing, and potential cures

    Screening strategies, including newborn screening and cost-benefit considerations

    Role of polymers in disease progression

    Gaps in treatment access and need for healthcare reform


    Professor Gerry McElvaney is a global leader in Alpha-1 research, founder of the Alpha-1 Foundation of Ireland, and Director of the Cystic Fibrosis Unit at Beaumont Hospital. His work has positioned Ireland at the forefront of Alpha-1 detection and research.


    Hosts:

    Dr Barry Harnedy – Respiratory trainee, Irish Thoracic Society Educational Officer

    Sandra Green – Respiratory fellow, co-founder of Irish Doctors for the Environment and ITS Podcast Productions



    Chapters (highlights):

    00:05 Intro | 01:00 Vaping & inflammation | 02:00 Diagnosis pitfalls

    03:20 Future therapies | 04:50 Screening importance | 07:00 Treatment advances

    10:00 Genetics explained | 12:00 Smoking impact | 13:40 Newborn screening

    16:00 Gene therapies | 17:30 Key takeaways


    Key message: Test comprehensively, detect early, intervene early, and remain optimistic about emerging therapies.


    References:

    Fraughen DD, et al. Am J Respir Crit Care Med. 2023;208:964–974.

    McElvaney NG, et al. Lancet Respir Med. 2017;5:51–60.

    Molloy K, et al. Am J Respir Crit Care Med. 2014;189:419–427.

    Franciosi AN, et al. Am J Respir Crit Care Med. 2020;202:73–82.

    Leacy EJ, et al. Am J Respir Crit Care Med. 2025;211:2408–2410.

    McElvaney OJ, et al. Med (N Y). 2022;3:233–248.

    Franciosi AN, et al. COPD. 2021;18:76–82.

    35 min
  • Inspire: From Bench to Bedside: The Journey of Professor Gerry McElvaney in Alpha-1 Research (Part 1)

    In this episode, we explore the remarkable career of Professor Gerry McElvaney, a world-leading figure in Alpha-1 antitrypsin deficiency research and translational medicine. Gerry shares his journey from clinical medicine to pioneering discovery science, revealing how curiosity, perseverance, and strategic thinking can drive real-world clinical breakthroughs.

    From building a research laboratory from scratch to establishing Ireland’s first national targeted detection programmes, Gerry reflects on the challenges of advocacy, diagnostics, and innovation. He discusses pioneering therapeutic development, lessons from high-profile research failures, and how unexpected influences—such as Dolly the sheep—shaped scientific understanding of protein therapies and treatment design.

    The conversation spans early detection, personalised medicine, gene editing, and the future of genetic lung disease, while also highlighting the human side of science: mentorship, multidisciplinary teamwork, patient-centred foundations, and the power of listening to clinical questions as the spark for transformative research.

    This episode is a masterclass in translational medicine—connecting bedside observations to laboratory discovery and back again—offering invaluable insight for clinicians, researchers, and early-career innovators.

    • Transition from clinical medicine to translational research

    • Establishing Ireland’s first Alpha-1 diagnostic and detection programmes
    • Advocacy with hospitals and government agencies
    • Lessons from gene therapy and research setbacks
    • Dolly the sheep and protein half-life discoveries
    • Funding strategies and research sustainability
    • Multidisciplinary team building
    • Patient foundations and community engagement
    • Future visions: early detection, AI, and gene editing
    • Translating ward-round questions into research breakthroughs


    Professor Gerry McElvaney is a world-renowned expert in Alpha-1 antitrypsin deficiency. He founded the Alpha-1 Foundation of Ireland and established Europe’s first national targeted detection programme. He is Director of the Cystic Fibrosis Unit at Beaumont Hospital, where his work spans cystic fibrosis, Alpha-1 antitrypsin deficiency, infection, and immunity. His leadership has transformed Ireland into a global hub for Alpha-1 research and patient care.

    Dr Barry Harnedy – Respiratory specialist trainee, digital innovation advocate, and current co-Educational Officer of the Irish Thoracic Society.

    Sandra Green – Irish-trained respiratory fellow, climate advocate, co-founder of Irish Doctors for the Environment, MSc in Leadership & Innovation in Healthcare at Royal College of Surgeons Ireland, and co-founder of Irish Thoracic Society Podcast Productions.


    00:00 Welcome & introduction

    05:46 National detection & screening journey
    09:34 Dolly the sheep & protein research
    12:30 Translational research in action
    17:21 Gender differences in CF outcomes
    27:05 Alpha-1 Foundation & community impact
    30:30 Future visions: AI & gene editing
    33:23 Advice for early-career clinicians

    36 min
  • Inspire (Part 2) – Professional Branding in Healthcare Careers with Sarah Geraghty

    In this episode, Sarah Geraghty shares clear, practical strategies for healthcare professionals who want to advance their careers with intention. From defining your personal brand to building meaningful networks, this conversation focuses on reflection, self-awareness, and strategic action as the foundations of sustainable growth in a demanding field.


    In this episode, we explore:

    -The most common mistake in healthcare career planning: an unclear personal brand.

    -How to define and communicate your professional brand effectively

    - The importance of self-awareness and aligning your actions with your brand

    - Practical steps to assess and close gaps between how you're perceived and how you want to be seen

    - Balancing technical expertise with communication skills for career progression

    - Customising your brand for different stakeholders and career stages

    - Building meaningful, high-quality relationships over superficial connections

    - The role of reflection and goal-setting in strategic career planning

    - Staying authentic while adapting your persona to different professional contexts


    Guest

    Sarah Geraghty is Head of Careers at The Communications Clinics, specialising in high-stakes interview preparation and career transitions. A seasoned communication trainer and coach, she blends practical storytelling with leadership development to help professionals articulate their value clearly and confidently.

    With a background in journalism and editorial work, including contributions to The Irish Times and The Journal, and experience as Assistant Editor of Gloss Magazine, Sarah brings real-world insight into performing under pressure in healthcare and beyond.


    Hosts

    Marissa O’Callaghan is an Irish-trained Respiratory Fellow currently undertaking a post-doc fellowship at Erasmus MC Rotterdam in the Netherlands. She completed Irish respiratory and internal medicine training and her PhD in 2025. Her interests include interstitial and rare lung diseases, clinical research, medical education, and medical innovation. Together with co-host Sandra Green, she founded the ITS podcast series in June 2024.


    Sandra Green is an Irish-trained respiratory doctor and climate advocate, and co-founder of Irish Doctors for the Environment. She holds an MSc in Leadership and Innovation in Healthcare from the Royal College of Surgeons Ireland (2023–2025). With Marissa, she co-founded the Irish Thoracic Society Podcast Productions in 2024 to share knowledge, insights, and innovation in respiratory care.


    Chapters:

    00:00 – Navigating Career Development in Healthcare

    01:56 – Understanding Professional Branding

    09:37 – The Importance of Communication Skills

    11:52 – Practical Steps for Building and Demonstrating Your Brand

    14:19 – Communicating Technical Skills and Intentional Self-Promotion

    18:23 – Staying Authentic While Adapting Your Brand

    21:42 – Actionable Steps for Career Advancement


    Resources & Links

    - Sarah Geraghty – LinkedIn: https://ie.linkedin.com/in/sarah-geraghty-comms

    - The Communication Clinic: https://www.communicationsclinic.ie/

    27 min

About Irish Thoracic Society Podcast Productions

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