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Akshay Desai and Amin Yehya discuss the newest JACC: Heart Failure Position Statement that proposes a pragmatic framework for defining clinically meaningful within-patient changes across heart failure outcomes to improve the patient-centeredness of care during shared decision-making. Learn more about the article: https://www.jacc.org/doi/10.1016/j.jchf.2026.103310
Dinesh Kalra, Andrew Choi, and G. B. John Mancini discuss the author group's post hoc analysis of the randomized NEWTON-CABG CardioLink-5 trial.
Audio Summary of three articles from the September 2026 issue of JACC: Advances.
In this episode, Frank Marchlinski, MD, Deputy Editor of JACC: Clinical Electrophysiology, discusses a study of ventricular tachycardia ablation in patients with active cardiac sarcoidosis. Using integrated FDG-PET and cardiac MRI imaging, the investigators found that VT exit sites were often located in areas of active inflammation, while more proximal circuit sites were associated with scar. Patients in whom only VT exit sites could be identified had substantially higher VT recurrence rates, suggesting that targeting deeper portions of the VT circuit may improve outcomes.
Nicole Bhave, Ashwini Kerkar, and Ahmed Kamal Siddiqi discuss what inspired this study, differences in mortality trends among age groups, and the most important takeaways from the paper.
In this episode, Frank Marchlinski, MD, Deputy Editor of JACC: Clinical Electrophysiology, discusses a study evaluating how CT-defined myocardial ridges and functional mapping can be combined to identify critical ablation targets in post-infarction ventricular tachycardia. The investigators found that VT target sites frequently localized to CT-defined ridges, particularly those associated with primary deceleration zones, suggesting that functional mapping can help distinguish active arrhythmogenic ridges from inactive ones and support more targeted VT ablation.
Commentary by Dr. Jian'an Wang.
Commentary by Dr. Jian'an Wang.
Commentary by Dr. Jian'an Wang.
Commentary by Dr. Jian'an Wang.
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