In this episode of the EADV Podcast, Dr. Antonio Torrelo speaks with Dr. Andrea Diociaiuti, contributor to the recent JEACP Special issue on cutaneous mosaicism, to explore one of the most fascinating concepts in dermatology and genetics. Together, they discuss how mosaicism shapes the skin, the clinical patterns that help physicians recognise these conditions, and how advances in genetic sequencing are transforming diagnosis and patient care. The conversation also delves into the broader implications of mosaicism beyond the skin, the importance of careful clinical observation, and the increasing potential of precision medicine and targeted therapies. This episode offers listeners an accessible and forward-looking overview of a rapidly evolving field that is changing the way dermatologists understand genetics, skin biology, and personalised medicine.

Read the Special Issue: https://onlinelibrary.wiley.com/toc/27686566/2025/4/3