Anatoly Chubais, a high-ranking Russian official who led the country’s post-Soviet economic reforms, has resigned from his post and fled the country in opposition to Russia’s invasion of Ukraine, news outlets reported Wednesday, making him the first high-level figure to officially distance himself from the Kremlin.

Chubais, 66, and his spouse have fled to Istanbul, according to Russian media outlet RBC. Late last month, Chubais posted a photo of Boris Nemtsov, a leading Russian opposition figure murdered on a Moscow bridge in 2015, on social media, which was interpreted as a sign of opposition to the war, according to media reports.

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