1732: Keto Research Roundup: Alzheimer’s Disease, Continuous Ketone Monitor, Pre-Fast Exercise Impact On Ketones

On today’s episode of Jimmy Makes Science Simple on the LLVLC Show, Jimmy peels back the layers on another stack of cutting edge keto research. “The side effects of the drugs they give people with Alzheimer’s can make quality of life difficult.” Jimmy Moore In this first clip Jimmy shares from a February 23, 2021 study published in the journal Alzheimer’s Research & Therapy entitled “Randomized crossover trial of a modified ketogenic diet in Alzheimer’s disease”: https://alzres.biomedcentral.com/articles/10.1186/s13195-021-00783-x New Zealand researchers at Waikato Hospital in Hamilton, New Zealand used a modified ketogenic diet over a 12-week period on patients with a diagnosed case of Alzheimer’s disease. Primary outcomes included basic cognitive tests and quality-of-life improvements. Secondary outcomes included cardiovascular risk marker changes. The ketogenic diet beat the low-fat one across the board! Next up Jimmy shares from an April 9, 2021 study published in the Journal of Diabetes Science and Technology entitled “Feasibility of Continuous Ketone Monitoring in Subcutaneous Tissue using a Ketone Sensor”: https://journals.sagepub.com/doi/full/10.1177/19322968211008185 At long last, a continuous ketone monitor (CKM) very similar to how a continuous glucose monitor (CGM) works is currently undergoing research and testing before coming to the market. Just like the CGM, the new CKM will not be measuring blood but rather interstitial fluid which is generally excepted as a proxy for blood readings. In the first-ever human trial of continuous ketone monitoring, they tested 12 healthy individuals eating a low-carb diet and wearing 3 CKM‘s over a 14-day period and comparing those readings to a finger prick blood ketone test (using the Precision Xtra device from Abbott). Watch this video to find out just how accurate the CKM is and a couple of questions that Jimmy has about this new technology. To wrap up this episode, Jimmy shares from a March 12, 2021 study published in the journal Medicine & Science in Sports & Exercise entitled “The Effects of Exercise on Beta-Hydroxybutyrate Concentrations over a 36-h Fast: A Randomized Crossover Study”: https://pubmed.ncbi.nlm.nih.gov/33731648