King's BHF Centre Podcast

In this episode, I had the pleasure of speaking with Professor Sharon Tooze, an expert in autophagy — a vital cellular process for cleaning out damaged components and recycling nutrients. She explained how autophagy responds to stress and plays a crucial role in health, with its dysfunction linked to neurological disorders like Alzheimer's and Parkinson's. We discussed the challenges of studying autophagy in humans, the paradox of its role in cancer, and the complexities of developing therapies that target this process. Her journey in research has been fascinating, potently connected to understanding organelle biogenesis, and I'm excited to see where her work leads next.