TV Personality Jack Osbourne and Oscar Award-winner for best short “Crisis Hotline: Veterans Dial 1” Dana Perry join Pat O’Brien and Andrew Spanswick.

Lead singer of the B-52s Kate Pierson and Academy Award-winner Lou Gossett, Jr. discuss how they overcame their addictions and maintain sobriety.

In honor of Valentine’s Day, relationship therapist Pat Allen and polyamorist Dedeker Winston talk sex, love, and addiction with Pat, Andrew, and special guest host Jennifer Giminez.

Former NFL Quarterback Todd Marinovich joins Pat O’Brien and special guest host Erica Spiegelman to discuss how addiction affected his life, and Marijuana Advocate Cheryl Shuman debates the addictive qualities of marijuana.

Media Mogul Shadoe Stevens joins Pat O’Brien and Andrew Spanswick in a conversation about his career as Top 40 Radio host, his addiction, and his over 30-year long sobriety.

Gary Stromberg, author and inspirational speaker, details his struggles with addiction and his road to recovery after life in the music business as owner of a high profile PR agency in the heart of Hollywood.

Jason Wahler, formerly of reality television shows “The Hills,” and “Laguna Beach,” discusses his addiction, his recovery, and his crusade to end the stigma of addiction.

TJennifer Giminez talks to guest host Dr. Giles and Pat O’Brien about her new project “Soberbook.com” being a woman in recovery, and getting through the holidays sober.

Highlights from previous shows featuring relationship expert Dr. Wendy Walsh, host and addiction specialist Dr. Drew, and Olympic figure skater Tai Babilonia.

Dr. Jason Giles and Dr. Adi Jaffe join Pat O’Brien in the studio to talk about what happens when doctors face their own addictions and different methodologies of addiction treatment.