Lab Rats to Unicorns

In this episode of Lab Rats to Unicorns, we welcome Dede Willis, co-founder and CEO of Orbit Genomics, a trailblazer in the field of diagnostics and life sciences. With a background in engineering and over 25 years of leadership experience, Dede shares how her engineering mindset and entrepreneurial resilience have driven her to build impactful startups that tackle complex challenges. 

Dede dives into the mission of Orbit Genomics, exploring how they’re harnessing the potential of “junk DNA” to revolutionize cancer detection and save lives. She also opens up about the challenges of securing funding in the diagnostics space, the importance of fostering team diversity, and the pivotal role government programs like ARPA-H and Cancer Moonshot play in advancing healthcare innovation. 

Through thoughtful storytelling and actionable insights, Dede reveals how diagnostics can complement therapeutics, why collaboration is essential to progress, and how startups can thrive by embracing resilience and adaptability. This episode is an inspiring testament to the power of persistence, innovation, and building bridges in science and beyond.

In this episode of Lab Rats to Unicorns: Rising Stars, we are joined by Dr. Gabe Kwong, a trailblazing biomedical engineer, innovator, and entrepreneur. Gabe is the director of the Laboratory for Synthetic Immunity at Georgia Tech and Emory University, where his groundbreaking research focuses on engineering immune cells as living drugs and developing cutting-edge diagnostics for early disease detection. 

Gabe shares his journey from academia to entrepreneurship, founding Glimpse Bio and Port Therapeutics to bring life-saving technologies from the lab to the market. He delves into the transformative potential of synthetic immunity and his work on the Cancer Moonshot initiative, which aims to create an activity-based cancer atlas and advance multi-cancer early detection. 

In this candid conversation, Gabe reflects on the importance of mentorship, the power of community spaces like Science Square in Atlanta, and the challenges of aligning science with market demands. Tune in to hear how Gabe is driving innovation, building bridges in the biotech ecosystem, and training the next generation of entrepreneurial researchers. This episode is an inspiring look at the intersection of science, innovation, and the human drive to make a difference. 

In this episode of Lab Rats to Unicorns, John Flavin sits down with Casey McPherson, a musician, songwriter, and rare disease advocate whose life took an extraordinary turn when his daughter, Rose, was diagnosed with HNRNPH2, an ultra-rare neurodevelopmental disorder. Best known for his work as the lead vocalist and songwriter for Alpha Rev and Flying Colors, Casey has spent much of his career crafting powerful music that resonates deeply with audiences. But when faced with the challenges of navigating the healthcare system for rare diseases, Casey turned his creativity, resilience, and determination toward a new mission: advancing precision medicine for underserved patient communities. 

As the founder of To Cure a Rose Foundation, Everlum Bio, and Chrysalis Genetics, Casey is revolutionizing the way treatments for rare diseases are approached. In this conversation, he shares how his experiences as an artist helped him find innovative ways to connect, problem-solve, and advocate for change in biotech. Casey’s journey is a testament to the power of resilience, collaboration, and the unwavering love of a parent determined to make a difference. 

Join us as Casey discusses his transition from music to medicine, the importance of collaboration in rare disease research, and how he’s working to create scalable solutions for patient communities that have been overlooked for far too long. This episode is an inspiring exploration of how passion and creativity can drive impact in even the most unexpected arenas. 

This episode of Lab Rats to Unicorns features an inspiring conversation with Julia Vitarello, founder of Mila’s Miracle Foundation and a trailblazer in the field of individualized genetic therapies. Julia shares the story of her daughter Mila, who was diagnosed with a rare and fatal genetic disease, Batten disease, at age six. Confronted with a system ill-equipped to handle ultra-rare conditions, Julia embarked on a transformative journey to develop Milasen, the first-ever genetic therapy tailored for a single individual. 

Through resilience and collaboration, Julia mobilized a global network of scientists, regulators, and supporters to create a treatment that set a precedent for a new approach in medicine. Beyond her daughter’s story, Julia reflects on the systemic barriers families face when accessing life-saving treatments and how her foundation is addressing these challenges. She explores the future of healthcare, advocating for changes to regulatory and reimbursement models to scale access to innovative therapies for rare disease communities. Julia’s pioneering work is a testament to the power of advocacy, science, and the unwavering determination of a mother to spark a revolution in medicine. 

In this episode, John Flavin sits down with Dr. Ivan Liachko, co-founder and CEO of Phase Genomics, a company at the forefront of genomics and microbiome research. Ivan shares his journey from a young immigrant fascinated by biology in Ukraine to a biotech leader based in Seattle. His academic path began with a keen interest in genetics, leading him to work at the University of Washington, where he honed skills in both genetics and computer science. Dr. Liachko discusses how Phase Genomics emerged from a passion project to solve unique biological challenges, evolving into a full-fledged company offering genome assembly services, microbiome diagnostics, and groundbreaking cancer diagnostic tools. Ivan’s focus on innovation is clear, as he reflects on the importance of courage, community, and resilience when transforming science into industry. As the conversation unfolds, Ivan delves into his vision for future scientific breakthroughs and the value of an ecosystem that supports unconventional thinking. 

In this insightful episode of Lab Rats to Unicorns, Steve Lehmann sits down with Dr. Zhenpeng Qin, Associate Professor of Mechanical and Bioengineering at the University of Texas at Dallas. Dr. Qin shares his groundbreaking work in biomedical engineering, focusing on the development of nanomaterials to advance diagnostics and therapeutic delivery. From innovations in nanoparticle technology to exploring the blood-brain barrier for treatment delivery, Dr. Qin’s journey reveals the power of interdisciplinary research. This episode dives into the evolution of his career, his shift from traditional mechanical engineering to medical applications, and his vision for the future of biomedical technology.

Join us for a conversation with Dr. Raghu Kalluri, a leading figure in cancer biology, who serves as the Chair of the Department of Cancer Biology at MD Anderson Cancer Center. With over 300 publications, multiple successful biotech ventures, and groundbreaking work in exosome research, Dr. Kalluri discusses the intricate relationship between science, medicine, and industry, his career path from researcher to entrepreneur, and his exciting vision for using innovation to transform cancer care. 

Join us on Lab Rats to Unicorns as we dive into the career of Michael Torres, CEO of Crossbridge Bio. With a Ph.D. in cancer biology and a background in equity research, Michael has been at the forefront of developing cutting-edge oncology treatments. In this episode, he discusses the evolution of antibody-drug conjugates (ADCs) and the process of building biotech companies in the Texas innovation ecosystem, as well as his personal journey from researcher to CEO. 

Join us on Lab Rats to Unicorns as we dive into the inspiring journey of Dr. Jochen Reiser, President of UTMB and CEO of UTMB Health System. A nephrologist, healthcare executive, and biotech entrepreneur, Jochen shares insights from his transition into the U.S. medical landscape, his pioneering research in kidney disease, and the founding of Walden Biosciences. This episode explores the exciting intersection of clinical care, research, and innovation. 

Key Topics:

• Jochen’s transition from Germany to the U.S. and his research in nephrology 
• Founding and commercializing Walden Biosciences for kidney disease 
• Leading UTMB as President and fostering innovation 
• Balancing clinical care, research, and education in healthcare 
• Collaboration and team-building in the biotechnology sector 

Join Steve Lehmann & Jeremy Langsam from Portal's Stargaze team on a bimonthly segment of Lab Rats to Unicorns: Rising Stars. In this episode, they explore the groundbreaking work of Zachi Attia, the Director of Artificial Intelligence at Mayo Clinic. With a rich background in electrical engineering and a Ph.D. in Bioinformatics, Zachi discusses his pivotal role in advancing AI models that predict and screen cardiovascular diseases. From his innovative research to real-world applications that are saving lives, this episode offers an inspiring look into the future of healthcare.